Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 7/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TK2 | O00142 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22198654 | 1.00 | TK1 (0.39) | TK1MAPK1HPGDTK2ALDH1A1 | |
| SCHEMBL26793575 | 0.94 | MAPK1 (0.41) | TK1MAPK1HPGDTK2ALDH1A1 | |
| SCHEMBL22260407 | 0.90 | MAPK1 (0.42) | TK1MAPK1HPGDTK2ALDH1A1 | |
| SCHEMBL22380811 | 0.88 | TK1 (0.47) | TK1MAPK1TK2ALDH1A1 | |
| SCHEMBL22260568 | 0.88 | TK1 (0.43) | TK1MAPK1HPGDTK2 | |
| SCHEMBL22020961 | 0.85 | TK1 (0.47) | TK1MAPK1TK2ALDH1A1 | |
| SCHEMBL22020875 | 0.84 | MAPK1 (0.41) | TK1MAPK1HPGDTK2ALDH1A1 | |
| SCHEMBL22946557 | 0.83 | SQOR (0.42) | ALDH1A1LMNAPOLB | |
| SCHEMBL22946803 | 0.83 | TK1 (0.47) | TK1MAPK1HPGDTK2ALDH1A1 | |
| SCHEMBL22946795 | 0.82 | TK1 (0.49) | TK1MAPK1HPGDTK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10696711-B2 | Asymmetric auxiliary group | WAVE LIFE SCIENCES LTD. (SG) | 2020-06-30 | — | — | US | disclosed |
| US-20190177357-A1 | ASYMMETRIC AUXILIARY GROUP | WAVE LIFE SCIENCES JAPAN (JP) | 2019-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190177357-A1 | ASYMMETRIC AUXILIARY GROUP | NIT2, IDH1, HBG2 | TK1 1751/4885MAPK1 1348/4885HPGD 856/4885 |
| US-10696711-B2 | Asymmetric auxiliary group | NIT2, IDH1, HBG2 | TK1 1751/4885MAPK1 1348/4885HPGD 856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.