Ddctp

Ddctp

SCHEMBL210922

Nc1ccn([C@H]2CC[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)n1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLG P54098 3/20 0.70
POLB P06746 1/20 0.55
P2RY2 P41231 9/20 0.53
P2RY4 P51582 5/20 0.53
P2RY6 Q15077 5/20 0.53
P2RY12 Q9H244 2/20 0.45
CACNA1F O60840 1/20 0.43
LMNA P02545 1/20 0.43
ALB P02768 1/20 0.43
MAPT P10636 1/20 0.43
CACNA1D Q01668 1/20 0.43
CACNA1S Q13698 1/20 0.43
CACNA1C Q13936 1/20 0.43
PDE3A Q14432 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ddctp SCHEMBL30586989 1.00 POLG (0.70) POLGPOLBP2RY2P2RY4P2RY6
Ddctp SCHEMBL20879464 1.00 POLG (0.70) POLGPOLBP2RY2P2RY4P2RY6
Ddctp SCHEMBL16807754 1.00 POLG (0.70) POLGPOLBP2RY2P2RY4P2RY6
Ddctp SCHEMBL18840498 1.00 POLG (0.70) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL543438 0.98 POLG (0.67) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL543055 0.92 POLG (0.60) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL543054 0.92 POLG (0.60) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL1763274 0.91 POLG (0.59) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL23157013 0.90 POLG (0.55) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL21895844 0.90 POLG (0.55) POLGPOLBP2RY2P2RY4P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1949 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122095103-A Mutant DNA polymerase and methods of use thereof 2026-05-26 CN claimed
US-12630865-B2 Products and processes for multiplex nucleic acid identification AGENA BIOSCIENCE, INC. (US) 2026-05-19 US claimed
EP-4724455-A1 MULTIVALENT BINDING UNIT MODIFIED DIDEOXYNUCLEOTIDE TRIPHOSPHATES AND METHODS OF MAKING AND USING THE SAME ILLUMINA, INC. (US) 2026-04-15 EP claimed
US-12597490-B2 Methods and systems for modeling phasing effects in sequencing using termination chemistry Life Technologies Corporation (US) 2026-04-07 US claimed
WO-2025235939-A1 METHODS FOR BALANCED AMPLIFICATION OF SMALL SAMPLES OF NUCLEIC ACIDS ORCHID BIOSCIENCE, INC. (US) 2025-11-13 WO claimed
US-12454722-B2 Multiplexed method for the identification and quantitation of minor alleles and polymorphisms AGENA BIOSCIENCE, INC. (US) 2025-10-28 US claimed
EP-4605547-A1 NOISE REDUCTION FOR DATA STORAGE IN DNA Catalog Technologies, Inc. (US) 2025-08-27 EP claimed
WO-2025105897-A1 METHOD FOR DETECTING GENOMIC MUTATION THROUGH NUCLEIC ACID PATTERN-BASED PURIFICATION, AND DISEASE DIAGNOSIS METHOD USING SAME 광주과학기술원 2025-05-22 WO claimed
US-20250154557-A1 COMPOSITION FOR SELECTING NUCLEIC ACIDS OF INTEREST, AND A METHOD FOR SELECTING NUCLEIC ACIDS USING THEREOF GWANGJU INST SCIENCE & TECH (KR) 2025-05-15 US claimed
WO-2025042729-A1 CELL PREPARATION COMPOSITION, SYSTEM AND METHOD FOR SINGLE CELL TRANSCRIPTOMICS Life Technologies Corporation (US) 2025-02-27 WO claimed
EP-0496749-A4 SPECTRALLY RESOLVABLE RHODAMINE DYES FOR NUCLEIC ACID SEQUENCE DETERMINATION 1993-06-16 EP claimed
WO-1992022306-A1 TRANSFORMED ERYTHROCYTES, PROCESS FOR PREPARING THE SAME, AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS COMMUNAUTE ECONOMIQUE EUROPEENNE (CEE) (LU) 1992-12-23 WO claimed
EP-0496749-A1 SPECTRALLY RESOLVABLE RHODAMINE DYES FOR NUCLEIC ACID SEQUENCE DETERMINATION. APPLIED BIOSYSTEMS (US) 1992-08-05 EP claimed
EP-0286418-B1 ANTI-RETROVIRAL AGENTS AND DELIVERY SYSTEMS FOR THE SAME US COMMERCE (US) 1992-07-08 EP claimed
EP-0416011-A4 CHEMOTHERAPEUTIC COMPOSITION FOR AIDS US COMMERCE (US) 1991-05-22 EP claimed
WO-1991005060-A2 SPECTRALLY RESOLVABLE RHODAMINE DYES FOR NUCLEIC ACID SEQUENCE DETERMINATION APPLIED BIOSYSTEMS, INC. (US) 1991-04-18 WO claimed
EP-0416011-A1 CHEMOTHERAPEUTIC COMPOSITION FOR AIDS THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) 1991-03-13 EP claimed
WO-1989011274-A1 CHEMOTHERAPEUTIC COMPOSITION FOR AIDS THE UNITED STATES OF AMERICA, AS REPRESENTED BY TH (US) 1989-11-30 WO claimed
US-4879277-A 2',3'-DIDEOXYCYTIDINE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1989-11-07 US claimed
EP-0298280-A2 Animal derived cell with antigenic protein introduced therein HAPGOOD, C.V., a Netherlands Antilles Limited Partnership (US) 1989-01-11 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630865-B2 Products and processes for multiplex nucleic acid identification POLM, POLN, POLL POLG 128/4885POLB 6/4885P2RY2 2279/4885
US-12597490-B2 Methods and systems for modeling phasing effects in sequencing using termination chemistry RNGTT, TRHR, RIF1 POLG 140/4885POLB 13/4885P2RY2 1953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.