Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | EBP | Q15125 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20108584 | 0.85 | MAPK1 (0.42) | KCNH2SIGMAR1CYP2D6CYP1A2LTA4H | |
| SCHEMBL24389487 | 0.76 | KDM4E (0.31) | HRH3KDM4E | |
| SCHEMBL1129251 | 0.74 | EBP (0.50) | KCNH2EBPSIGMAR1MCHR1CYP2D6 | |
| SCHEMBL21093667 | 0.69 | LPL (0.58) | HTTKMT2AHTR2AHTR2CKDM4E | |
| SCHEMBL21674328 | 0.69 | EBP (0.53) | KCNH2EBPSIGMAR1MCHR1CYP2D6 | |
| SCHEMBL9706125 | 0.67 | EBP (0.72) | KCNH2EBPSIGMAR1MCHR1CYP2D6 | |
| SCHEMBL10251067 | 0.67 | LPL (0.41) | LTA4HPTGS1PDE4A | |
| SCHEMBL23635245 | 0.66 | LPL (0.38) | ESR2 | |
| SCHEMBL20569274 | 0.66 | HRH3 (0.35) | HRH3DRD3KDM4E | |
| SCHEMBL12513174 | 0.66 | EBP (0.44) | KCNH2EBPSIGMAR1MCHR1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562155-B1 | HYDROXAMIC ACID DERIVATIVE | TAISHO PHARMACEUTICAL CO LTD (JP) | 2019-06-05 | — | — | EP | disclosed |