SCHEMBL210942

SCHEMBL210942

O=Cc1ccc(OCCBr)cc1

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.58
SMN1; SMN2 Q16637 3/20 0.58
MAPT P10636 2/20 0.58
HPGD P15428 2/20 0.58
LMNA P02545 2/20 0.58
CYP2A6 P11509 1/20 0.48
KDM4E B2RXH2 3/20 0.46
RAB9A P51151 1/20 0.45
ALDH1A3 P47895 1/20 0.44
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.42
STS P08842 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
DRD1 P21728 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL586117 0.90 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
SCHEMBL31603834 0.89 ALDH1A1 (0.51) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
SCHEMBL2182381 0.88 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
SCHEMBL851166 0.87 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
SCHEMBL302663 0.86 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
SCHEMBL302512 0.86 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
SCHEMBL20211763 0.86 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
SCHEMBL2184223 0.86 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
SCHEMBL8551794 0.85 ALDH1A1 (0.69) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
SCHEMBL8204708 0.85 ALDH1A1 (0.75) ALDH1A1SMN1; SMN2MAPTHPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119971404-A Fire extinguishing agent and preparation method thereof 宋炜 2025-05-13 CN claimed
CN-118546293-A Modified polyacrylamide containing degradable hydrophobic monomer and preparation method thereof 西南石油大学 2024-08-27 CN claimed
CN-117747739-A Preparation method of ionic compound and supermolecular skeleton assembly, artificial solid electrolyte interface phase and zinc metal anode 吉林大学 2024-03-22 CN claimed
CN-117343319-A Cationic polyamide-amine flocculant containing degradable imine bond and preparation method and application thereof 西南石油大学 2024-01-05 CN claimed
CN-116023298-A PH responsive surfactant with dynamic imine bond, and preparation and application thereof 中国石油化工股份有限公司 2023-04-28 CN claimed
CN-115232319-A Supermolecule polyaldehyde compound based on poly-beta-cyclodextrin and ferrocene host-guest action and preparation method thereof 四川大学 2022-10-25 CN claimed
CN-115160454-A Supermolecule polyaldehyde compound based on poly-beta-cyclodextrin and adamantane host-guest action and preparation method thereof 四川大学 2022-10-11 CN claimed
CN-111514107-B Active oxygen response type vesicle and preparation method thereof 江南大学 2021-12-21 CN claimed
CN-111514107-A Active oxygen response type vesicle and preparation method thereof 江南大学 2020-08-11 CN claimed
US-20070142427-A1 Noncyclic 1,3-Dicarbonyl compounds as dual PPAR agonists with potent antihyperglycemic and antihyperlipidemic activity SHENZHEN CHIPSCREEN BIOSCIENCES LTD. (CN) 2007-06-21 US claimed
US-20070099942-A1 AZA nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases BIOCRYST PHARMACEUTICALS, INC. (US) 2007-05-03 US claimed
US-7192970-B2 Noncyclic 1,3-dicarbonyl compounds as dual PPAR agonists with potent antihyperglycemic and antihyperlipidemic activity CHIPSCREEN BIOSCIENCES, LTD. (CN) 2007-03-20 US claimed
US-20040138211-A1 Noncyclic 1,3-dicarbonyl compounds as dual PPAR agonists with potent antihyperglycemic and antihyperlipidemic activity SHENZHEN CHIPSCREEN BIOSCIENCES LTD. (CN) 2004-07-15 US claimed
WO-2004048338-A1 NONCYCLIC 1,3-DICARBONYL COMPOUNDS AS DUAL PPAR AGONISTS WITH POTENT ANTIHYPERGLYCEMIC AND ANTIHYPERLIPIDEMIC ACTIVITY SHENZHEN CHIPSCREEN BIOSCIENCES LTD. (US) 2004-06-10 WO claimed
US-20260102390-A1 4-(2-(4-((2,4-DIOXOTHIAZOLIDIN-5-YL)METHYL)PHENOXY) DERIVATIVES AS PPARgamma AGONISTS AND AUTOTAXIN INHIBITORS FOR USE IN THE TREATMENT OF FIBROSIS UNI-PHARMA KLEON TSETIS PHARMACEUTICAL LABORATORIES S.A. (GR) 2026-04-16 US disclosed
CN-121226640-A Polymer gel profile control system and preparation method thereof 西南石油大学 2025-12-30 CN disclosed
EP-4637734-A1 4-(2-(4-((2,4-DIOXOTHIAZOLIDIN-5-YL)METHYL)PHENOXY) DERIVATIVES AS PPARy AGONISTS AND AUTOTAXIN INHIBITORS FOR USE IN THE TREATMENT OF FIBROSIS Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. (GR) 2025-10-29 EP disclosed
US-4983633-A Amide compounds, process for preparing the same, and composition for activating gastric motor function containing the same HOKURIKU PHARMACEUTICAL CO., LTD. (JP) 1991-01-08 US disclosed
EP-0306827-A1 Amide compounds, process for preparing the same, and composition for activating gastric motor function containing the same Hokuriku Pharmaceutical Co.,Ltd (JP) 1989-03-15 EP disclosed
US-4465684-A ANTIDIABETIC, ANTILIPEMIC AGENT BAYER AKTIENGESELLSCHAFT (DE) 1984-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070142427-A1 Noncyclic 1,3-Dicarbonyl compounds as dual PPAR agonists with potent antihyperglycemic and antihyperlipidemic activity GPR119, PPARG, PPARA ALDH1A1 3570/4885SMN1; SMN2 4879/4885MAPT 4832/4885
US-20070099942-A1 AZA nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases NSUN2, NSUN3, POLR2H ALDH1A1 3520/4885SMN1; SMN2 1141/4885MAPT 4865/4885
US-20040138211-A1 Noncyclic 1,3-dicarbonyl compounds as dual PPAR agonists with potent antihyperglycemic and antihyperlipidemic activity PPARG, GPR119, PPARA ALDH1A1 3236/4885SMN1; SMN2 4870/4885MAPT 4836/4885
US-20260102390-A1 4-(2-(4-((2,4-DIOXOTHIAZOLIDIN-5-YL)METHYL)PHENOXY) DERIVATIVES AS PPARgamma AGONISTS AND AUTOTAXIN INHIBITORS FOR USE IN THE TREATMENT OF FIBROSIS PPARG, FABP1, PPARA ALDH1A1 1965/4885SMN1; SMN2 221/4885MAPT 2542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.