Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683647 | 0.72 | RAB9A (0.40) | RAB9ALMNANPC1ALDH1A1HPGD | |
| SCHEMBL7537282 | 0.69 | HSP90AB1 (0.48) | RAB9ALMNANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL19027606 | 0.69 | HSP90AA1 (0.46) | RAB9ALMNANPC1ALDH1A1HSP90AA1 | |
| SCHEMBL21303107 | 0.61 | GAA (0.62) | RAB9ALMNANPC1ALDH1A1HPGD | |
| SCHEMBL87256 | 0.61 | — | — | |
| SCHEMBL10971273 | 0.61 | HSP90AA1 (0.64) | LMNAALDH1A1HPGDHSP90AA1KMT2A | |
| SCHEMBL16644177 | 0.59 | HSP90AB1 (0.67) | RAB9ALMNANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18304964 | 0.59 | KMT2A (0.38) | RAB9ALMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL19422365 | 0.59 | HSP90AB1 (0.36) | HSP90AA1HTT | |
| SCHEMBL459298 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019115609-A1 | SACCHARIDE FUNCTIONALISED CARBABORANE CONJUGATES OF HUMAN PEPTIDE Y | UNIVERSITÄT LEIPZIG (DE) | 2019-06-20 | — | — | WO | disclosed |