SCHEMBL7537282

SCHEMBL7537282

CSc1nc(SC)nc(SC)n1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSP90AB1 P08238 2/20 0.48
MAPK1 P28482 2/20 0.37
HSP90AA1 P07900 4/20 0.37
PKM P14618 1/20 0.36
HTT P42858 3/20 0.34
KDM4E B2RXH2 2/20 0.34
LMNA P02545 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
ABCB1 P08183 1/20 0.34
ALDH1A1 P00352 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MAPT P10636 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
NPC1 O15118 1/20 0.32
XBP1 P17861 1/20 0.32
RAB9A P51151 1/20 0.32
PAX8 Q06710 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16644177 0.86 HSP90AB1 (0.67) HSP90AB1MAPK1HSP90AA1PKMHTT
SCHEMBL18790076 0.83 HSP90AB1 (0.39) HSP90AB1MAPK1HSP90AA1PKM
SCHEMBL383476 0.83 ALDH1A1 (0.41) HSP90AB1MAPK1HSP90AA1HTTKDM4E
SCHEMBL8071682 0.83 HSP90AB1 (0.71) HSP90AB1HSP90AA1ABCB1
SCHEMBL19027606 0.78 HSP90AA1 (0.46) HSP90AB1MAPK1HSP90AA1HTTKDM4E
SCHEMBL10920178 0.78 LMNA (0.55) HSP90AB1MAPK1HTTKDM4ELMNA
SCHEMBL19422365 0.78 HSP90AB1 (0.36) HSP90AB1HSP90AA1HTT
SCHEMBL19000175 0.78 HSP90AB1 (0.67) HSP90AB1MAPK1HSP90AA1PKMHTT
SCHEMBL16643891 0.76 HSP90AB1 (0.34) HSP90AB1HSP90AA1
SCHEMBL6765323 0.75 ALDH1A1 (0.50) HSP90AB1MAPK1HSP90AA1HTTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118050398-A Sand forest poison gas sensor and calibration device and calibration method thereof 沈星科技(深圳)有限公司 2024-05-17 CN claimed
CN-118050398-A Sand forest poison gas sensor and calibration device and calibration method thereof 沈星科技(深圳)有限公司 2024-05-17 CN disclosed
CN-118050398-A Sand forest poison gas sensor and calibration device and calibration method thereof 沈星科技(深圳)有限公司 2024-05-17 CN disclosed
US-20200385582-A1 CURABLE COMPOSITION, CURED PRODUCT, COLOR FILTER, METHOD FOR PRODUCING COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2020-12-10 US disclosed
US-7576036-B2 Heat-sensitive recording material, heat-sensitive recording method and method for manufacturing heat-sensitive recording material FUJIFILM CORPORATION (JP) 2009-08-18 US disclosed
US-20070032381-A1 Heat-sensitive recording material, heat-sensitive recording method and method for manufacturing heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2007-02-08 US disclosed
US-20070004594-A1 Heat-sensitive recording material and heat-sensitive recording method FUJI PHOTO FILM CO., LTD. 2007-01-04 US disclosed
EP-0711760-B1 METHOD OF ALKYLATING TRIAZINE DERIVATIVE NISSAN CHEMICAL IND LTD (JP) 2002-05-15 EP disclosed
EP-0882720-B1 METHODS FOR MODIFYING 1,3,5-TRIAZINE DERIVATIVES NISSAN CHEMICAL IND LTD (JP) 2001-08-22 EP disclosed
US-6130332-A USING A GROUP 8 METAL CATALYST AND ALDEHYDES OR KETONE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2000-10-10 US disclosed
US-6127538-A HYDROXYALKYLATION OF A TRIAMINO TRIAZINE DERIVATIVE HAVING AT LEAST ONE REACTIVE NITROGEN BY REACTING WHILE HEATING WITH AN ALKANEDIOL OR ITS ADDUCT IN THE PRESENCE OF HYDROGEN AND A METAL CATALYST; BY-PRODUCT INHIBITION NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2000-10-03 US disclosed
US-6124381-A CURING ACCELERATOR IS A 2-((MONO- OR DI-ALKYL)AMINO, MORPHOLINO, PIPERIDINO, METHYL OR PHENYL)-4,6-SUBSTITUTED DIAMINO-1,3,5-TRIAZINE OF GIVEN FORMULA; POT LIFE, STORAGE STABILITY, AND WORKABILITY NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2000-09-26 US disclosed
US-5998573-A TRIAZINE DERIVATIVE AND FORMALDEHYDE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1999-12-07 US disclosed
EP-0882720-A1 METHODS FOR MODIFYING 1,3,5-TRIAZINE DERIVATIVES NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1998-12-09 EP disclosed
US-5792867-A Method of alkylating of triazine derivatives NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1998-08-11 US disclosed
EP-0852241-A1 NOVEL AMINO RESIN COMPOSITIONS NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1998-07-08 EP disclosed
EP-0834523-A1 EPOXY/ACID ANHYDRIDE COMPOSITION NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1998-04-08 EP disclosed
EP-0760369-A1 PROCESS FOR ALKYLATING TRIAZINE DERIVATIVE NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1997-03-05 EP disclosed
EP-0711760-A1 METHOD OF ALKYLATING TRIAZINE DERIVATIVE NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1996-05-15 EP disclosed