SCHEMBL21096352

SCHEMBL21096352

CC(C)(C)OC(=O)NCCCC[C@H](N)c1nc(CC2CCCCC2)no1

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
BMP1 P13497 13/20 0.41
MEN1 O00255 5/20 0.40
KMT2A Q03164 5/20 0.40
ALDH1A1 P00352 1/20 0.40
EPHX1 P07099 1/20 0.39
SRC P12931 1/20 0.38
MMP1 P03956 1/20 0.38
MMP3 P08254 1/20 0.38
MMP13 P45452 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21096353 1.00 BMP1 (0.41) BMP1MEN1KMT2AALDH1A1EPHX1
SCHEMBL21097060 0.97 BMP1 (0.42) BMP1MEN1KMT2AEPHX1SRC
SCHEMBL21096373 0.97 BMP1 (0.42) BMP1MEN1KMT2AEPHX1SRC
Acetic Acid SCHEMBL21062730 0.94 BMP1 (0.41) BMP1MEN1KMT2AEPHX1SRC
Acetic Acid SCHEMBL21062734 0.94 BMP1 (0.41) BMP1MEN1KMT2AEPHX1SRC
SCHEMBL25468943 0.90 BMP1 (0.42) BMP1MEN1KMT2AALDH1A1EPHX1
SCHEMBL25468976 0.87 BMP1 (0.42) BMP1MEN1KMT2AEPHX1SRC
SCHEMBL21062820 0.85 BMP1 (0.44) BMP1SRCMMP1MMP3MMP13
SCHEMBL21062823 0.85 BMP1 (0.44) BMP1SRCMMP1MMP3MMP13
SCHEMBL26604281 0.84 MEN1 (0.43) MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240059734-A1 MITOCHONDRIA-TARGETING PEPTIDES STEALTH BIOTHERAPEUTICS INC. 2024-02-22 US disclosed
US-11795196-B2 Mitochondria-targeting peptides STEALTH BIOTHERAPEUTICS INC. (US) 2023-10-24 US disclosed
US-11795196-B2 Mitochondria-targeting peptides STEALTH BIOTHERAPEUTICS INC. (US) 2023-10-24 US disclosed
US-11795196-B2 Mitochondria-targeting peptides STEALTH BIOTHERAPEUTICS INC. (US) 2023-10-24 US disclosed
EP-4218785-A2 MITOCHONDRIA-TARGETING PEPTIDES Stealth BioTherapeutics Inc. (US) 2023-08-02 EP disclosed
EP-4218785-A2 MITOCHONDRIA-TARGETING PEPTIDES Stealth BioTherapeutics Inc. (US) 2023-08-02 EP disclosed
US-20230146515-A1 MITOCHONDRIA-TARGETING PEPTIDES STEALTH BIOTHERAPEUTICS INC. 2023-05-11 US disclosed
US-20230146515-A1 MITOCHONDRIA-TARGETING PEPTIDES STEALTH BIOTHERAPEUTICS INC. 2023-05-11 US disclosed
US-20230146515-A1 MITOCHONDRIA-TARGETING PEPTIDES STEALTH BIOTHERAPEUTICS INC. 2023-05-11 US disclosed
EP-3723783-B1 MITOCHONDRIA-TARGETING PEPTIDES STEALTH BIOTHERAPEUTICS INC (US) 2023-02-15 EP disclosed
EP-3723783-B1 MITOCHONDRIA-TARGETING PEPTIDES STEALTH BIOTHERAPEUTICS INC (US) 2023-02-15 EP disclosed
CN-111954539-A Mitochondrial targeting peptides 隐形生物治疗公司 2020-11-17 CN disclosed
WO-2019118878-A1 MITOCHONDRIA-TARGETING PEPTIDES STEALTH BIOTHERAPEUTICS CORP. (MC) 2019-06-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11795196-B2 Mitochondria-targeting peptides HSPE1, TFAM, TNNI3 BMP1 3539/4885MEN1 4795/4885KMT2A 4820/4885
US-20240059734-A1 MITOCHONDRIA-TARGETING PEPTIDES HSPE1, TFAM, TNNI3 BMP1 3539/4885MEN1 4795/4885KMT2A 4820/4885
US-20230146515-A1 MITOCHONDRIA-TARGETING PEPTIDES HSPE1, TFAM, TNNI3 BMP1 3539/4885MEN1 4795/4885KMT2A 4820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.