SCHEMBL21097066 — predicted protein targets

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	MAOA	P21397	13/20	0.81

▸	MAOB	P27338	2/20	0.81

▸	CALML3	P27482	5/20	0.49

▸	CYP2C19	P33261	2/20	0.47

▸	CYP2C9	P11712	1/20	0.47

▸	CYP3A4	P08684	1/20	0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL1383497	0.91	MAOA (0.84)	MAOAMAOBCALML3CYP2C19CYP2C9
SCHEMBL17447335	0.91	MAOA (0.83)	MAOAMAOBCALML3CYP2C19CYP2C9
SCHEMBL1990275	0.90	MAOA (0.82)	MAOAMAOBCALML3CYP2C19CYP2C9
SCHEMBL17801670	0.90	MAOA (0.82)	MAOAMAOBCALML3CYP2C19CYP2C9
Tedizolid SCHEMBL29833257	0.89	MAOA (1.00)	MAOAMAOBCALML3CYP2C19CYP2C9
Tedizolid SCHEMBL440398	0.89	MAOA (1.00)	MAOAMAOBCALML3CYP2C19CYP2C9
Tedizolid SCHEMBL3807996	0.89	MAOA (1.00)	MAOAMAOBCALML3CYP2C19CYP2C9
Tedizolid SCHEMBL31385281	0.89	MAOA (1.00)	MAOAMAOBCALML3CYP2C19CYP2C9
Tedizolid SCHEMBL29380875	0.89	MAOA (1.00)	MAOAMAOBCALML3CYP2C19CYP2C9
SCHEMBL20216092	0.89	MAOA (0.81)	MAOAMAOBCALML3CYP2C19CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2019118311-A1	PHARMACEUTICAL COMPOSITIONS OF TEDIZOLID PHOSPHATE	MERCK SHARP & DOHME CORP. (US)	2019-06-20	—	—	WO	disclosed