SCHEMBL20216092

Cn1nnc(-c2ccc(-c3ccc(N4CC(COP(=O)(O)OC[C@H]5CN(c6ccc(-c7ccc(-c8nnn(C)n8)nc7)c(F)c6)C(=O)O5)OC4=O)cc3F)cn2)n1

nearest known ligand 0.81

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	MAOA	P21397	12/20	0.81

▸	MAOB	P27338	2/20	0.81

▸	CALML3	P27482	6/20	0.49

▸	CYP2C19	P33261	2/20	0.47

▸	CYP2C9	P11712	1/20	0.47

▸	CYP3A4	P08684	1/20	0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL13144441	1.00	MAOA (0.81)	MAOAMAOBCALML3CYP2C19CYP2C9
SCHEMBL12991629	0.97	MAOA (0.78)	MAOAMAOBCALML3CYP2C19CYP2C9
Tedizolid Phosphate SCHEMBL29766931	0.96	MAOA (0.79)	MAOAMAOBCALML3CYP2C19CYP2C9
Tedizolid Phosphate SCHEMBL1990278	0.96	MAOA (0.79)	MAOAMAOBCALML3CYP2C19CYP2C9
Tedizolid Phosphate SCHEMBL29377855	0.96	MAOA (0.79)	MAOAMAOBCALML3CYP2C19CYP2C9
Tedizolid Phosphate SCHEMBL1557561	0.96	MAOA (0.79)	MAOAMAOBCALML3CYP2C19CYP2C9
SCHEMBL1990275	0.96	MAOA (0.82)	MAOAMAOBCALML3CYP2C19CYP2C9
SCHEMBL13144426	0.95	MAOA (0.76)	MAOAMAOBCALML3CYP2C19CYP2C9
SCHEMBL12997802	0.95	MAOA (0.78)	MAOAMAOBCALML3CYP2C19CYP2C9
SCHEMBL12997803	0.95	MAOA (0.78)	MAOAMAOBCALML3CYP2C19CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-9988406-B2	Forms of R)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate	MERCK SHARP & DOHME CORP. (US)	2018-06-05	—	—	US	disclosed