Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | FGF2 | P09038 | 1/20 | 0.33 |
| ▸ | IDUA | P35475 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18334882 | 0.78 | IDUA (0.33) | IDUAKAT2ASUCNR1 | |
| SCHEMBL16750226 | 0.76 | SUCNR1 (0.35) | APLNRIDUASUCNR1 | |
| SCHEMBL29740164 | 0.75 | IDUA (0.33) | APLNRIDUASUCNR1 | |
| SCHEMBL13858344 | 0.75 | IDUA (0.33) | APLNRIDUASUCNR1 | |
| SCHEMBL21695641 | 0.74 | IDUA (0.30) | IDUA | |
| SCHEMBL15355541 | 0.72 | SLC5A1 (0.36) | — | |
| SCHEMBL19806791 | 0.70 | IDUA (0.31) | IDUASUCNR1 | |
| SCHEMBL31028169 | 0.70 | SUCNR1 (0.36) | IDUASUCNR1 | |
| SCHEMBL16076771 | 0.69 | PYGB (0.45) | — | |
| SCHEMBL23247975 | 0.68 | IDUA (0.38) | IDUASUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019118571-A1 | ISOXAZOLE ANALOGS AS FXR AGONISTS AND METHODS OF USE THEREOF | ENANTA PHARMACEUTICALS, INC. (US) | 2019-06-20 | — | — | WO | disclosed |