Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.48 |
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.33 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21592104 | 0.83 | TLR8 (0.51) | TLR8TLR7NR1I3 | |
| SCHEMBL17843455 | 0.83 | TLR8 (0.68) | TLR8TLR7 | |
| SCHEMBL30006352 | 0.78 | TLR8 (0.48) | TLR8AAK1BCL2BECN1BACE1 | |
| SCHEMBL1235939 | 0.78 | TLR8 (0.48) | TLR8AAK1BCL2BECN1BACE1 | |
| SCHEMBL2333056 | 0.77 | TLR8 (0.51) | TLR8AAK1TLR7BCL2BECN1 | |
| SCHEMBL16592799 | 0.76 | TLR8 (0.42) | TLR8AAK1BCL2BECN1BACE1 | |
| SCHEMBL16592818 | 0.76 | TLR8 (0.41) | TLR8AAK1BCL2BECN1BACE1 | |
| SCHEMBL25688112 | 0.72 | TLR8 (0.69) | TLR8TLR7 | |
| SCHEMBL28467264 | 0.72 | BACE1 (0.37) | TLR8AAK1BCL2BECN1BACE1 | |
| SCHEMBL18659723 | 0.72 | TLR8 (0.68) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019118884-A1 | ANTIBODY CONSTRUCT-DRUG CONJUGATE FOR THE TREATMENT OF HEPATITIS | SILVERBACK THERAPEUTICS, INC. (US) | 2019-06-20 | — | — | WO | disclosed |