Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.48 |
| ▸ | BCL2 | P10415 | 7/20 | 0.35 |
| ▸ | BACE1 | P56817 | 3/20 | 0.35 |
| ▸ | BECN1 | Q14457 | 3/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1235939 | 1.00 | TLR8 (0.48) | TLR8BCL2BACE1BECN1AAK1 | |
| SCHEMBL21098295 | 0.87 | TLR8 (0.48) | TLR8NPC1RAB9ABRD9 | |
| SCHEMBL2333056 | 0.87 | TLR8 (0.51) | TLR8BCL2BACE1BECN1AAK1 | |
| SCHEMBL16592818 | 0.85 | TLR8 (0.41) | TLR8BCL2BACE1BECN1AAK1 | |
| SCHEMBL17843455 | 0.84 | TLR8 (0.68) | TLR8 | |
| SCHEMBL27175788 | 0.81 | TLR8 (0.36) | TLR8AAK1LCK | |
| SCHEMBL16592799 | 0.79 | TLR8 (0.42) | TLR8BCL2BACE1BECN1AAK1 | |
| SCHEMBL1238110 | 0.79 | TLR8 (0.55) | TLR8 | |
| SCHEMBL28467264 | 0.79 | BACE1 (0.37) | TLR8BCL2BACE1BECN1AAK1 | |
| SCHEMBL18759358 | 0.78 | TLR8 (0.35) | TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117801107-A | Benzazepine derivatives, conjugates containing same and application thereof | 上海迪诺医药科技有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115448917-A | Nitrogen-containing compound, conjugate containing nitrogen-containing compound and application of conjugate | 上海迪诺医药科技有限公司 | 2022-12-09 | — | — | CN | disclosed |