Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | KLK7 | P49862 | 3/20 | 0.46 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24799782 | 0.94 | CTSK (0.48) | KLK7KLK5CTSKPPARAPPARG | |
| SCHEMBL21098326 | 0.94 | CTSK (0.48) | KLK7KLK5CTSKPPARAPPARG | |
| SCHEMBL17949814 | 0.89 | BCHE (0.48) | ACEKLK7KLK5BCHEACHE | |
| SCHEMBL16478619 | 0.89 | BCHE (0.48) | ACEKLK7KLK5BCHEACHE | |
| SCHEMBL17489335 | 0.89 | CTSK (0.54) | KLK7KLK5BCHEACHECTSK | |
| SCHEMBL21098346 | 0.86 | ACE (0.41) | ACEBCHEACHECTSSCTSL | |
| SCHEMBL17486773 | 0.85 | CTSK (0.49) | KLK7KLK5CTSKPPARAPPARG | |
| SCHEMBL23475267 | 0.84 | PPARA (0.52) | ACEKLK7KLK5BCHEACHE | |
| SCHEMBL16472134 | 0.84 | ACE (0.50) | ACEKLK7KLK5BCHEACHE | |
| SCHEMBL24945913 | 0.83 | ACE (0.55) | ACEKLK7KLK5BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4180438-A1 | 18F-LABELED PSMA-TARGETED PET IMAGING AGENTS | Cancer Targeted Technology LLC (US) | 2023-05-17 | — | — | EP | disclosed |
| EP-3560937-A1 | 18F-LABELED PSMA-TARGETED PET IMAGING AGENTS | Cancer Targeted Technology LLC (US) | 2019-10-30 | — | — | EP | disclosed |
| EP-2970345-B1 | 18F-LABELED PSMA-TARGETED PET IMAGING AGENTS | CANCER TARGETED TECH LLC (US) | 2019-06-19 | — | — | EP | disclosed |