Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 4/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21099229 | 0.77 | KMT2A (0.41) | BRD4KDM4EPOLBMEN1NPC1 | |
| SCHEMBL21098772 | 0.76 | BRD4 (0.39) | BRD4SLC2A1PDK2MEN1NPC1 | |
| SCHEMBL21098795 | 0.75 | MAOB (0.44) | MAOBHRH3PPARDMAOAPPARG | |
| SCHEMBL21098941 | 0.74 | MAOA (0.49) | MAOBKDM4EPOLBPPARDMAOA | |
| SCHEMBL21052076 | 0.71 | BRD4 (0.71) | BRD4MAOBHRH3MAOAPDE3B | |
| SCHEMBL22815609 | 0.66 | BRD4 (0.82) | BRD4MAOBHRH3MAOAPDE3B | |
| SCHEMBL20010711 | 0.65 | CYP1A2 (0.49) | THRBALDH1A1MAPTKMT2A | |
| SCHEMBL21098679 | 0.64 | MAOB (0.63) | MAOBHRH3MAOA | |
| SCHEMBL24101995 | 0.64 | CYP1A2 (0.43) | THRBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL18458260 | 0.63 | KMT2A (0.39) | GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019109188-A1 | ACYL HYDRAZONE LINKERS, METHODS AND USES THEREOF | ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR) (CA) | 2019-06-13 | — | — | WO | disclosed |