Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21099075 | 0.96 | MAPK1 (0.49) | MAPK1TSHRHSD17B10DHODHMEN1 | |
| SCHEMBL19009466 | 0.93 | TSHR (0.49) | MAPK1TSHRHSD17B10DHODHMEN1 | |
| SCHEMBL18679989 | 0.92 | MAPK1 (0.46) | MAPK1TSHRHSD17B10DHODHMEN1 | |
| SCHEMBL21099079 | 0.92 | HSD17B10 (0.48) | MAPK1TSHRHSD17B10DHODHMEN1 | |
| SCHEMBL20195347 | 0.92 | KDM4E (0.44) | MAPK1TSHRHSD17B10DHODHMEN1 | |
| SCHEMBL21098923 | 0.89 | HSD17B10 (0.42) | MAPK1TSHRHSD17B10DHODHKDM4E | |
| SCHEMBL18680021 | 0.88 | MAPK1 (0.47) | MAPK1TSHRHSD17B10DHODHMEN1 | |
| SCHEMBL18680016 | 0.88 | MAPK1 (0.47) | MAPK1TSHRHSD17B10DHODHMEN1 | |
| SCHEMBL21099054 | 0.87 | MAPK1 (0.43) | MAPK1TSHRHSD17B10DHODHMEN1 | |
| SCHEMBL21099056 | 0.87 | KDM4E (0.46) | MAPK1TSHRHSD17B10DHODHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10323006-B2 | Heterocyclic compound and organic light emitting element using same | LG CHEM, LTD. (KR) | 2019-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10323006-B2 | Heterocyclic compound and organic light emitting element using same | CRY1, CRY2, NR2E3 | MAPK1 3653/4885TSHR 3517/4885HSD17B10 2186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.