⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18881181 | 0.78 | — | — | |
| SCHEMBL4288201 | 0.75 | — | — | |
| SCHEMBL2190290 | 0.75 | — | — | |
| SCHEMBL5415498 | 0.75 | — | — | |
| SCHEMBL10992058 | 0.73 | LMNA (0.32) | — | |
| SCHEMBL8257534 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL27762047 | 0.73 | — | — | |
| SCHEMBL13588069 | 0.73 | — | — | |
| SCHEMBL19867154 | 0.73 | — | — | |
| SCHEMBL21898698 | 0.71 | CYP1A2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021250531-A1 | 4-(4,5-DIHYDRO-1H-PYRAZOL-1-YL)PYRIMIDINE COMPOUND AS CANNABINOID RECEPTOR (CB1 RECEPTOR) ANTAGONISTS AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | 주식회사 종근당 | 2021-12-16 | — | — | WO | disclosed |
| CN-109952295-A | A kind of CDK4/6 inhibitor and its preparation method and application | 江苏豪森药业集团有限公司 | 2019-06-28 | — | — | CN | disclosed |
| EP-2986313-B1 | STABLE, PROTRACTED GLP-1/GLUCAGON RECEPTOR CO-AGONISTS FOR MEDICAL USE | NOVO NORDISK AS (DK) | 2019-06-12 | — | — | EP | disclosed |