⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2190290 | 0.75 | — | — | |
| SCHEMBL21099641 | 0.75 | — | — | |
| SCHEMBL7925132 | 0.73 | — | — | |
| SCHEMBL8257534 | 0.73 | — | — | |
| SCHEMBL13588069 | 0.73 | — | — | |
| SCHEMBL10992058 | 0.73 | LMNA (0.32) | — | |
| Hydrochloric Acid SCHEMBL27762047 | 0.73 | — | — | |
| SCHEMBL7821222 | 0.71 | — | — | |
| SCHEMBL8471567 | 0.71 | CRBN (0.39) | — | |
| SCHEMBL14152046 | 0.71 | MAPT (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014104209-A1 | NOVEL BENZAZEPINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | 株式会社 三和化学研究所 (JP) | 2014-07-03 | — | — | WO | disclosed |
| EP-1560837-B1 | NOVEL AMPIPHILIC DERIVATIVES OF ALPHA-C-PHENYL N-TERT-BUTYL NITRONE | TS PHARMA (FR) | 2009-08-05 | — | — | EP | disclosed |
| EP-0330247-B1 | N-HYDROXY-ALPHA-AMINO ACIDS, AMIDES AND OTHER DERIVATIVES THEREOF | DSM N.V. (NL) | 1993-07-07 | — | — | EP | disclosed |
| US-5101036-A | PROCESS FOR THE PREPARATION OF N-HYDROXY-ALPHA-AMINO ACID AMIDES | STAMICARBON B.V. (NL) | 1992-03-31 | — | — | US | disclosed |
| US-5072041-A | OPTICALLY ACTIVE N-HYDROXY-ALPHA-AMINO ACIDS, AMIDES AND THEIR DERIVATIVES | STAMICARBON B.V. (NL) | 1991-12-10 | — | — | US | disclosed |
| EP-0330247-A1 | N-hydroxy-alpha-amino acids, amides and other derivatives thereof | DSM N.V. (NL) | 1989-08-30 | — | — | EP | disclosed |