Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | ASAH1 | Q13510 | 5/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | WNT1 | P04628 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | UGCG | Q16739 | 1/20 | 0.39 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29411602 | 0.87 | ALDH1A1 (0.48) | HTR3AKDM1AMAOAMAOBMEN1 | |
| SCHEMBL21045499 | 0.87 | ALDH1A1 (0.48) | HTR3AKDM1AMAOAMAOBMEN1 | |
| SCHEMBL21045324 | 0.72 | NAMPT (0.48) | GRIA4ASAH1MEN1ALDH1A1CYP3A4 | |
| SCHEMBL29411378 | 0.72 | NAMPT (0.48) | GRIA4ASAH1MEN1ALDH1A1CYP3A4 | |
| SCHEMBL21045114 | 0.71 | FKBP1A (0.57) | POLB | |
| SCHEMBL21045115 | 0.71 | FKBP1A (0.57) | POLB | |
| SCHEMBL29411452 | 0.71 | FKBP1A (0.57) | POLB | |
| SCHEMBL21045374 | 0.71 | ALDH1A1 (0.47) | HTR3AGRIA4ASAH1MEN1ALDH1A1 | |
| SCHEMBL21045199 | 0.71 | ALDH1A1 (0.47) | HTR3AGRIA4ASAH1MEN1ALDH1A1 | |
| SCHEMBL21045200 | 0.71 | ALDH1A1 (0.47) | HTR3AGRIA4ASAH1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113242-A1 | TUBULIN INHIBITORS | Lin BioScience, LLC (US) | 2019-06-13 | — | — | WO | disclosed |