Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ACKR3 | P25106 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21045273 | 0.84 | HIF1A (0.49) | POLBALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL29411386 | 0.84 | HIF1A (0.49) | POLBALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL29411602 | 0.78 | ALDH1A1 (0.48) | TP53POLBLMNAKDM4EALDH1A1 | |
| SCHEMBL21045499 | 0.78 | ALDH1A1 (0.48) | TP53POLBLMNAKDM4EALDH1A1 | |
| SCHEMBL21100326 | 0.73 | POLB (0.39) | TP53POLBLMNAKDM4EALDH1A1 | |
| SCHEMBL29411378 | 0.72 | NAMPT (0.48) | TP53POLBKDM4EALDH1A1MEN1 | |
| SCHEMBL21045324 | 0.72 | NAMPT (0.48) | TP53POLBKDM4EALDH1A1MEN1 | |
| SCHEMBL29411623 | 0.71 | MAPT (0.47) | TP53ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21045387 | 0.71 | MAPT (0.47) | TP53ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21045396 | 0.70 | HIF1A (0.50) | ALDH1A1MEN1KMT2ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113242-A1 | TUBULIN INHIBITORS | Lin BioScience, LLC (US) | 2019-06-13 | — | — | WO | disclosed |