Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | WNT1 | P04628 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21100605 | 0.82 | POLB (0.39) | POLBLMNAKDM4ENPC1 | |
| SCHEMBL21045499 | 0.81 | ALDH1A1 (0.48) | POLBTP53MAPTHPGDTSHR | |
| SCHEMBL29411602 | 0.81 | ALDH1A1 (0.48) | POLBTP53MAPTHPGDTSHR | |
| SCHEMBL21100380 | 0.73 | TP53 (0.48) | POLBTP53LMNAKDM4EALDH1A1 | |
| SCHEMBL29411365 | 0.73 | SMN1; SMN2 (0.47) | MAPTHPGDTSHRASAH1HSD17B10 | |
| SCHEMBL21045194 | 0.73 | SMN1; SMN2 (0.47) | MAPTHPGDTSHRASAH1HSD17B10 | |
| SCHEMBL21100366 | 0.70 | HTR3A (0.41) | POLBTP53WNT1DYRK1AMAPT | |
| SCHEMBL21045324 | 0.69 | NAMPT (0.48) | POLBTP53MAPTTSHRASAH1 | |
| SCHEMBL29411378 | 0.69 | NAMPT (0.48) | POLBTP53MAPTTSHRASAH1 | |
| SCHEMBL21045396 | 0.68 | HIF1A (0.50) | MAPTTSHRASAH1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113242-A1 | TUBULIN INHIBITORS | Lin BioScience, LLC (US) | 2019-06-13 | — | — | WO | disclosed |