SCHEMBL3424602

SCHEMBL3424602

Nc1ccn([C@@]2(O)C[C@H](O)[C@@H](CO)O2)c(=O)n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE3A Q14432 3/20 0.47
PDE4D Q08499 1/20 0.47
SLC29A1 Q99808 1/20 0.47
LMNA P02545 5/20 0.47
MTOR P42345 2/20 0.47
THRB P10828 1/20 0.47
MDM2 Q00987 1/20 0.47
NCOA1 Q15788 1/20 0.47
NCOA3 Q9Y6Q9 1/20 0.47
CACNA1F O60840 2/20 0.40
ALB P02768 2/20 0.40
MAPT P10636 2/20 0.40
CACNA1D Q01668 2/20 0.40
CACNA1S Q13698 2/20 0.40
CACNA1C Q13936 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.37
POLB P06746 2/20 0.37
ALDH1A1 P00352 2/20 0.37
DNMT1 P26358 2/20 0.36
ADRB1 P08588 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28379714 0.85 PDE3A (0.47) PDE3APDE4DSLC29A1LMNAMTOR
SCHEMBL1939478 0.85 PDE3A (0.47) PDE3APDE4DSLC29A1LMNAMTOR
SCHEMBL7794942 0.84 PDE3A (0.46) PDE3APDE4DSLC29A1LMNAMTOR
SCHEMBL992472 0.84 PDE3A (0.46) PDE3APDE4DSLC29A1LMNAMTOR
SCHEMBL3038818 0.84 PDE3A (0.52) PDE3APDE4DSLC29A1LMNAMTOR
SCHEMBL51650 0.84 PDE3A (0.46) PDE3APDE4DSLC29A1LMNAMTOR
SCHEMBL4971926 0.84 PDE3A (0.46) PDE3APDE4DSLC29A1LMNAMTOR
SCHEMBL3449198 0.84 PDE3A (0.46) PDE3APDE4DSLC29A1LMNAMTOR
SCHEMBL27544566 0.84 PDE3A (0.46) PDE3APDE4DSLC29A1LMNAMTOR
SCHEMBL2118776 0.83 PDE3A (0.46) PDE3APDE4DSLC29A1LMNAMTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7790374-B2 Process for sequence saturation mutagenesis (SeSaM) BASF AKTIENGESELLSCHAFT (DE) 2010-09-07 US claimed
EP-1670914-B1 A PROCESS FOR SEQUENCE SATURATION MUTAGENESIS (SESAM) BASF AG (DE) 2008-01-23 EP claimed
EP-1812456-A2 ß-L-N4-HYDROXYCYTOSINE DEOXYNUCLEOSIDES AND THEIR USE AS PHARMACEUTICAL AGENTS IN THE PROPHYLAXIS OR THERAPY OF VIRAL DISEASES MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN (DE) 2007-08-01 EP claimed
US-20060223148-A1 Process for sequence saturation mutagenesis (sesam) BASF AKTIENGESCHAFT (DE) 2006-10-05 US claimed
EP-1670914-A1 A PROCESS FOR SEQUENCE SATURATION MUTAGENESIS (SESAM) BASF AKTIENGESELLSCHAFT (DE) 2006-06-21 EP claimed
WO-2006045616-A2 β-L-N4-HYDROXYCYTOSINE DEOXYNUCLEOSIDES AND THEIR USE AS PHARMACEUTICAL AGENTS IN THE PROPHYLAXIS OR THERAPY OF VIRAL DISEASES Max-Delbrück-Centrum für Molekulare Medizin (DE) 2006-05-04 WO claimed
WO-2005035757-A1 A PROCESS FOR SEQUENCE SATURATION MUTAGENESIS (SESAM) BASF AKTIENGESELLSCHAFT (DE) 2005-04-21 WO claimed
US-20260125669-A1 METHODS AND COMPOSITIONS FOR SYNTHETIC EVOLUTION UNIVERSITAT POMPEU FABRA (ES) 2026-05-07 US disclosed
EP-4599047-A1 METHODS AND COMPOSITIONS FOR SYNTHETIC EVOLUTION Universitat Pompeu Fabra (ES) 2025-08-13 EP disclosed
WO-2024074709-A1 METHODS AND COMPOSITIONS FOR SYNTHETIC EVOLUTION UNIVERSITAT POMPEU FABRA (ES) 2024-04-11 WO disclosed
US-7790374-B2 Process for sequence saturation mutagenesis (SeSaM) BASF AKTIENGESELLSCHAFT (DE) 2010-09-07 US disclosed
EP-1670914-B1 A PROCESS FOR SEQUENCE SATURATION MUTAGENESIS (SESAM) BASF AG (DE) 2008-01-23 EP disclosed
US-20060223148-A1 Process for sequence saturation mutagenesis (sesam) BASF AKTIENGESCHAFT (DE) 2006-10-05 US disclosed
EP-1670914-A1 A PROCESS FOR SEQUENCE SATURATION MUTAGENESIS (SESAM) BASF AKTIENGESELLSCHAFT (DE) 2006-06-21 EP disclosed
WO-2005035757-A1 A PROCESS FOR SEQUENCE SATURATION MUTAGENESIS (SESAM) BASF AKTIENGESELLSCHAFT (DE) 2005-04-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125669-A1 METHODS AND COMPOSITIONS FOR SYNTHETIC EVOLUTION POLM, CPSF6, CPSF1 PDE3A 4739/4885PDE4D 4481/4885SLC29A1 736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.