Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.36 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.36 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21100474 | 0.81 | P2RX7 (0.42) | NPC1RAB9ASMN1; SMN2USP2CNR1 | |
| SCHEMBL21045128 | 0.77 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2USP2L3MBTL1 | |
| SCHEMBL21045185 | 0.76 | SMN1; SMN2 (0.48) | NPC1RAB9ASMN1; SMN2USP2L3MBTL1 | |
| SCHEMBL29411475 | 0.76 | SMN1; SMN2 (0.48) | NPC1RAB9ASMN1; SMN2USP2L3MBTL1 | |
| SCHEMBL29411613 | 0.72 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2USP2L3MBTL1 | |
| SCHEMBL21045597 | 0.72 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2USP2L3MBTL1 | |
| SCHEMBL29411494 | 0.72 | HDAC3 (0.47) | NPC1RAB9ASMN1; SMN2USP2L3MBTL1 | |
| SCHEMBL21045144 | 0.72 | HDAC3 (0.47) | NPC1RAB9ASMN1; SMN2USP2L3MBTL1 | |
| SCHEMBL21100616 | 0.70 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2USP2L3MBTL1 | |
| SCHEMBL21045385 | 0.70 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2USP2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113242-A1 | TUBULIN INHIBITORS | Lin BioScience, LLC (US) | 2019-06-13 | — | — | WO | disclosed |