Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21100475 | 0.81 | NPC1 (0.41) | SMN1; SMN2CNR1ROCK2ROCK1JAK2 | |
| SCHEMBL21045225 | 0.77 | SMN1; SMN2 (0.49) | P2RX7HPGDSMN1; SMN2CNR1NPC1 | |
| SCHEMBL29411490 | 0.77 | SMN1; SMN2 (0.49) | P2RX7HPGDSMN1; SMN2CNR1NPC1 | |
| SCHEMBL21045413 | 0.77 | PDK1 (0.43) | P2RX7HPGDSMN1; SMN2CNR1ROCK2 | |
| SCHEMBL21118917 | 0.74 | HPGD (0.41) | P2RX7HPGDSMN1; SMN2CNR1ROCK2 | |
| SCHEMBL21045267 | 0.73 | DHODH (0.48) | P2RX7HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL29411513 | 0.73 | DHODH (0.48) | P2RX7HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL21100619 | 0.73 | SMN1; SMN2 (0.48) | P2RX7HPGDSMN1; SMN2CNR1ROCK2 | |
| SCHEMBL21100313 | 0.72 | SMN1; SMN2 (0.47) | P2RX7HPGDSMN1; SMN2NPC1MEN1 | |
| SCHEMBL21100614 | 0.71 | SMN1; SMN2 (0.46) | P2RX7HPGDSMN1; SMN2NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113242-A1 | TUBULIN INHIBITORS | Lin BioScience, LLC (US) | 2019-06-13 | — | — | WO | disclosed |