4-Guanidino-Benzoic Acid

4-Guanidino-Benzoic Acid

SCHEMBL211005

N=C(N)Nc1ccc(C(=O)O)cc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.57
PRSS1 P07477 1/20 0.57
PRSS2 P07478 1/20 0.57
PRSS3 P35030 1/20 0.57
TMPRSS6 Q8IU80 1/20 0.57
ST14 Q9Y5Y6 1/20 0.57
ALDH1A1 P00352 1/20 0.53
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
MITF O75030 1/20 0.52
FFAR1 O14842 1/20 0.50
TP53 P04637 1/20 0.50
TSHR P16473 1/20 0.50
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
PTPN11 Q06124 1/20 0.49
EPHX2 P34913 1/20 0.49
NR1H4 Q96RI1 1/20 0.49
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Guanidino-Benzoic Acid SCHEMBL10674543 0.98 F2 (0.55) F2PRSS1PRSS2PRSS3TMPRSS6
4-Guanidino-Benzoic Acid SCHEMBL22127093 0.98 F2 (0.55) F2PRSS1PRSS2PRSS3TMPRSS6
4-Guanidino-Benzoic Acid SCHEMBL11123754 0.98 F2 (0.55) F2PRSS1PRSS2PRSS3TMPRSS6
4-Guanidino-Benzoic Acid SCHEMBL273175 0.98 F2 (0.55) F2PRSS1PRSS2PRSS3TMPRSS6
4-Guanidino-Benzoic Acid SCHEMBL28796971 0.96 F2 (0.53) F2PRSS1PRSS2PRSS3TMPRSS6
4-Guanidino-Benzoic Acid SCHEMBL22127091 0.96 F2 (0.58) F2PRSS1PRSS2PRSS3TMPRSS6
4-Guanidino-Benzoic Acid SCHEMBL7563601 0.91 CA2 (0.50) F2PRSS1PRSS2PRSS3TMPRSS6
4-Guanidino-Benzoic Acid SCHEMBL19205978 0.91 CA2 (0.50) F2PRSS1PRSS2PRSS3TMPRSS6
4-Guanidino-Benzoic Acid SCHEMBL9303333 0.89 F2 (0.61) F2PRSS1PRSS2PRSS3TMPRSS6
SCHEMBL11569991 0.85 KMT2A (0.54) F2PRSS1PRSS2PRSS3TMPRSS6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1002 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121586379-A Preparation method of high-quality perovskite thick film for X-ray detector 中国矿业大学 2026-02-27 CN claimed
US-12408548-B2 Perovskite layer, fabrication method and use the same CITY UNIVERSITY OF HONG KONG (HK) 2025-09-02 US claimed
CN-119947554-A Perovskite layer, manufacturing method thereof and solar cell 香港城市大学 2025-05-06 CN claimed
US-20250143173-A1 PEROVSKITE LAYER, FABRICATION METHOD AND USE THE SAME CITY UNIVERSITY OF HONG KONG (HK) 2025-05-01 US claimed
CN-119390614-A Preparation method of nafamostat mesylate 河北广祥制药有限公司 2025-02-07 CN claimed
CN-119143635-A Method for preparing nafamostat mesylate 北京诺康达医药科技股份有限公司 2024-12-17 CN claimed
CN-119143634-A Preparation method of nafamostat mesylate 北京诺康达医药科技股份有限公司 2024-12-17 CN claimed
US-20240226128-A1 NOVEL COMPOUNDS WITH DUAL INHIBITION ACTIVITY AGAINST SARS-COV-2 CRITICAL ENZYMES RDRP, MPRO AND HUMAN TMPRSS2 UNIVERSITY OF SHARJAH (AE) 2024-07-11 US claimed
CN-117986161-A Synthesis method of high-purity anti-hemagglutination medicament 华仁医学研究(安徽)有限公司 2024-05-07 CN claimed
CN-117986571-A Hyperbranched poly (beta-amino ester) with different groups at tail ends, and preparation method and application thereof 西安交通大学 2024-05-07 CN claimed
EP-0222608-A2 Derivatives of p-guanidinobenzoic acid and pharmaceutical agents containing them as active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 1987-05-20 EP claimed
EP-0214429-A1 Benzoyl esters KOWA CO. LTD. (JP) 1987-03-18 EP claimed
EP-0048433-B1 NOVEL AMIDINE COMPOUNDS, PROCESS FOR PRODUCING SAME AND ANTI-COMPLEMENT AGENT COMPRISING THEM TORII & CO., LTD. (JP) 1986-05-28 EP claimed
EP-0170180-A1 Substituted guanidinobenzoic-acid phenyl esters, process for their production and their use as pharmaceutical preparations SCHERING AKTIENGESELLSCHAFT (DE) 1986-02-05 EP claimed
EP-0024780-B1 MEDICATED INTRAUTERINE DEVICES Shaw, Seth Thomas, Jr. (US) 1984-10-17 EP claimed
EP-0024779-B1 DRUGS FOR USE WITH INTRAUTERINE DEVICES AND INTRAUTERINE DEVICES CONTAINING SAID DRUGS Shaw, Seth Thomas, Jr. (US) 1984-10-17 EP claimed
EP-0024781-B1 MEDICATED INTRAUTERINE DEVICES Shaw, Seth Thomas, Jr. (US) 1984-08-08 EP claimed
EP-0009879-B1 ENZYME DERIVATIVES FOR USE IN THE TREATMENT OF VENOUS THROMBOSIS, COMPOSITIONS CONTAINING THEM AND THEIR PREPARATION BEECHAM GROUP PLC (GB) 1983-10-12 EP claimed
EP-0028489-B1 ENZYME DERIVATIVES, AND THEIR PREPARATION BEECHAM GROUP PLC (GB) 1983-10-05 EP claimed
US-4258030-A ENZYME INHIBITOR AS STABILIZER ZERIA-SHINYAKU KOGYO KABUSHIKI KAISHA (JP) 1981-03-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250143173-A1 PEROVSKITE LAYER, FABRICATION METHOD AND USE THE SAME KCNQ1, KCNQ2, SCNN1B F2 4794/4885PRSS1 2304/4885PRSS2 2422/4885
US-12408548-B2 Perovskite layer, fabrication method and use the same KCNQ1, KCNQ2, SCNN1B F2 4794/4885PRSS1 2304/4885PRSS2 2422/4885
US-20240226128-A1 NOVEL COMPOUNDS WITH DUAL INHIBITION ACTIVITY AGAINST SARS-COV-2 CRITICAL ENZYMES RDRP, MPRO AND HUMAN TMPRSS2 TMPRSS2, ACE2, TMPRSS4 F2 2611/4885PRSS1 10/4885PRSS2 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.