Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | PTAFR | P25105 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4B | O94953 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21045402 | 0.80 | KDM4B (0.46) | SMN1; SMN2HPGDPTAFRNPC1RAB9A | |
| SCHEMBL29411607 | 0.80 | KDM4B (0.46) | SMN1; SMN2HPGDPTAFRNPC1RAB9A | |
| SCHEMBL21100618 | 0.80 | KDM4E (0.55) | PTAFRALDH1A1PSEN1PSEN2APH1B | |
| SCHEMBL21045196 | 0.79 | ROCK2 (0.49) | SMN1; SMN2HPGDPTAFRNPC1RAB9A | |
| SCHEMBL29411659 | 0.79 | ROCK2 (0.49) | SMN1; SMN2HPGDPTAFRNPC1RAB9A | |
| SCHEMBL21045197 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2HPGDPTAFRNPC1RAB9A | |
| SCHEMBL21045077 | 0.79 | POLB (0.43) | SMN1; SMN2HPGDPTAFRNPC1RAB9A | |
| SCHEMBL21045225 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2HPGDNPC1RAB9AP2RX7 | |
| SCHEMBL29411490 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2HPGDNPC1RAB9AP2RX7 | |
| SCHEMBL21045121 | 0.78 | SMN1; SMN2 (0.43) | SMN1; SMN2HPGDPTAFRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113242-A1 | TUBULIN INHIBITORS | Lin BioScience, LLC (US) | 2019-06-13 | — | — | WO | disclosed |