Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21101104 | 0.88 | SIGMAR1 (0.50) | KDM1ASIGMAR1DRD2MAOBHTR2A | |
| SCHEMBL21101190 | 0.88 | KDM1A (0.53) | KDM1ASIGMAR1DRD2MAOBHTR2A | |
| SCHEMBL12821659 | 0.84 | KDM1A (0.74) | KDM1ADRD2MAOBHTR2ASLC6A4 | |
| SCHEMBL12813712 | 0.84 | KDM1A (0.74) | KDM1ADRD2MAOBHTR2ASLC6A4 | |
| SCHEMBL19725557 | 0.84 | KDM1A (0.67) | KDM1ADRD2MAOBHTR2ASLC6A4 | |
| SCHEMBL21101256 | 0.81 | SIGMAR1 (0.52) | KDM1ASIGMAR1DRD2MAOBHTR2A | |
| SCHEMBL21101194 | 0.80 | MCHR1 (0.56) | KDM1ASIGMAR1DRD2MAOBHTR2A | |
| SCHEMBL21101342 | 0.80 | CYP2D6 (0.60) | KDM1ASIGMAR1DRD2MAOBHTR2A | |
| SCHEMBL28169202 | 0.78 | CXCR4 (0.68) | KDM1ASIGMAR1MAOBHTR2AMEN1 | |
| SCHEMBL28246592 | 0.77 | HTT (0.55) | SIGMAR1MEN1KMT2ATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2688568-B1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2019-06-19 | — | — | EP | disclosed |