Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3284430 | 0.87 | CA2 (0.59) | CA2MAPK1SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL3288965 | 0.87 | CA2 (0.59) | CA2MAPK1SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL9423046 | 0.85 | CA2 (0.65) | CA2MAPK1SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL2359678 | 0.83 | PLA2G2C (0.61) | PLA2G2CTDP1FFAR4FFAR1GPR84 | |
| SCHEMBL21896390 | 0.83 | CA2 (0.53) | CA2MAPK1SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL3286240 | 0.82 | CA2 (0.61) | CA2MAPK1SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL9073396 | 0.81 | MAPT (0.45) | PLA2G2CTDP1AKR1B1FFAR4FFAR1 | |
| SCHEMBL9629705 | 0.81 | FFAR4 (0.53) | PLA2G2CTDP1AKR1B1FFAR4FFAR1 | |
| SCHEMBL3285631 | 0.80 | CHRM1 (0.56) | CA2MAPK1SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL1930750 | 0.80 | CA2 (0.63) | CA2MAPK1SLC1A2SLC1A1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3498368-A1 | ALIPHATIC ZR-, HF-, AND LN-BASED INORGANIC-ORGANIC HYBRID SOLID MOF MATERIALS, METHODS FOR PREPARING SAME AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2019-06-19 | — | — | EP | disclosed |