Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CHKA | P35790 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.38 |
| ▸ | TPSD1 | Q9BZJ3 | 3/20 | 0.38 |
| ▸ | TPSG1 | Q9NRR2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1502093 | 0.81 | ALDH1A1 (0.52) | ALDH1A1CA2CHKAHSD11B1HPGD | |
| SCHEMBL30440562 | 0.80 | CHRM3 (0.46) | NCF1CHRM2CHRM1CHRM3PLG | |
| SCHEMBL22676984 | 0.79 | ALDH1A1 (0.50) | ALDH1A1CA2CHKAHSD11B1HPGD | |
| SCHEMBL30056243 | 0.79 | ALDH1A1 (0.56) | ALDH1A1CA2CHKAHSD11B1HPGD | |
| SCHEMBL4723863 | 0.79 | CHRM2 (0.38) | NCF1CHRM2CHRM1CHRM3PLG | |
| SCHEMBL3935701 | 0.78 | NCF1 (0.48) | NCF1CHRM2CHRM1CHRM3PLG | |
| SCHEMBL600521 | 0.78 | PLG (0.50) | NCF1CHRM2CHRM1CHRM3PLG | |
| SCHEMBL23651895 | 0.77 | NCF1 (0.46) | NCF1CHRM2CHRM1CHRM3PLG | |
| SCHEMBL22882344 | 0.77 | CPN1 (0.50) | ALDH1A1NCF1CHRM2CHRM1CHRM3 | |
| SCHEMBL20300505 | 0.77 | ALDH1A1 (0.50) | ALDH1A1CA2CHKAHSD11B1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2688568-B1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2019-06-19 | — | — | EP | disclosed |