Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 7/20 | 0.69 |
| ▸ | FAP | Q12884 | 6/20 | 0.50 |
| ▸ | DPP4 | P27487 | 2/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.47 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21101295 | 0.87 | PREP (0.68) | PREPFAPDPP4DPP9 | |
| SCHEMBL21101486 | 0.83 | PREP (0.67) | PREPFAP | |
| SCHEMBL21101477 | 0.83 | PREP (0.61) | PREPFAPDPP4DPP9TRPV1 | |
| SCHEMBL16267531 | 0.82 | PREP (1.00) | PREPFAPDPP4DPP9 | |
| SCHEMBL15138749 | 0.82 | PREP (1.00) | PREPFAPDPP4DPP9 | |
| SCHEMBL26225738 | 0.79 | FAP (0.58) | PREPFAPDPP4DPP9 | |
| SCHEMBL24928106 | 0.78 | FAP (0.73) | PREPFAP | |
| SCHEMBL21257036 | 0.76 | FAP (0.76) | PREPFAPDPP4DPP9 | |
| SCHEMBL21263980 | 0.75 | FAP (0.58) | PREPFAPDPP4DPP9 | |
| SCHEMBL21101632 | 0.75 | PREP (0.66) | PREPFAPDPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2804859-B1 | NOVEL FAP INHIBITORS | UNIV ANTWERPEN (BE) | 2019-06-12 | — | — | EP | disclosed |