Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 2/20 | 0.31 |
| ▸ | AHR | P35869 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16500762 | 0.73 | KDM4E (0.40) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL21574905 | 0.70 | KDM4E (0.32) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL21912966 | 0.69 | KDM4E (0.33) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL22084923 | 0.66 | KDM4E (0.36) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL14756555 | 0.66 | TAAR1 (0.35) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL23430369 | 0.66 | KDM4E (0.36) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL21010314 | 0.66 | KDM4E (0.33) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL19298979 | 0.65 | KDM4E (0.34) | ALDH1A1KDM4EPRKDCMEN1KMT2A | |
| SCHEMBL21479663 | 0.64 | MAOA (0.53) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL20982285 | 0.64 | CA1 (0.35) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2993215-B1 | Azabenzimidazo[2,1-a]benzimidazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2019-06-19 | — | — | EP | disclosed |