Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | TNKS | O95271 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.30 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21101340 | 0.69 | ALDH1A1 (0.35) | KDM4EALDH1A1MAOAGLACYP3A4 | |
| SCHEMBL24363546 | 0.69 | KDM4E (0.32) | KDM4EALDH1A1MAOAGLACYP3A4 | |
| SCHEMBL23737366 | 0.69 | KDM4E (0.32) | KDM4EALDH1A1MAOAGLACYP3A4 | |
| SCHEMBL23314339 | 0.69 | KDM4E (0.32) | KDM4EALDH1A1MAOAGLACYP3A4 | |
| SCHEMBL23430369 | 0.63 | KDM4E (0.36) | KDM4EALDH1A1MAOAGLACYP3A4 | |
| SCHEMBL23676600 | 0.63 | ALDH1A1 (0.33) | KDM4EALDH1A1MAOAGLACYP3A4 | |
| SCHEMBL18711547 | 0.62 | KDM4E (0.35) | KDM4EALDH1A1MAOAGLACYP3A4 | |
| SCHEMBL20982285 | 0.61 | CA1 (0.35) | KDM4EALDH1A1MAOAGLACYP3A4 | |
| SCHEMBL21007436 | 0.60 | KDM4E (0.33) | KDM4EALDH1A1MAOAGLACYP3A4 | |
| SCHEMBL16500762 | 0.60 | KDM4E (0.40) | KDM4EALDH1A1MAOAGLACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640252-A1 | 4H-IMIDAZO[1,2-A]IMIDAZOLES FOR ELECTRONIC APPLICATIONS | UDC Ireland Limited (IE) | 2020-04-22 | — | — | EP | disclosed |