Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23205040 | 0.82 | KDM1A (0.40) | KDM1AHRH3HSD11B1GNAO1 | |
| SCHEMBL4378930 | 0.81 | HSD11B1 (0.39) | KDM1AHRH3HSD11B1GNAO1 | |
| SCHEMBL6750686 | 0.79 | HRH3 (0.49) | KDM1AHRH3HSD11B1GNAO1 | |
| SCHEMBL4376655 | 0.77 | ACHE (0.44) | KDM1AGBA1HRH3HSD11B1ALDH1A1 | |
| SCHEMBL4376649 | 0.77 | HSD11B1 (0.39) | KDM1AHRH3HSD11B1GNAO1 | |
| SCHEMBL4380526 | 0.77 | KDM1A (0.39) | KDM1AGBA1HSD11B1ALDH1A1 | |
| SCHEMBL20154540 | 0.76 | HRH3 (0.52) | KDM1AHRH3GNAO1 | |
| SCHEMBL12449623 | 0.75 | KDM1A (0.38) | KDM1AGBA1HSD11B1ALDH1A1 | |
| SCHEMBL4371147 | 0.75 | HRH3 (0.39) | KDM1AHRH3HSD11B1GNAO1ALDH1A1 | |
| SCHEMBL4371150 | 0.75 | GBA1 (0.41) | KDM1AGBA1HRH3HSD11B1GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2688568-B1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2019-06-19 | — | — | EP | disclosed |