Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.32 |
| ▸ | CHRNG | P07510 | 1/20 | 0.32 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CHRND | Q07001 | 1/20 | 0.32 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963321 | 0.66 | CES2 (0.54) | CES2CES1RAB9AMAOAMAOB | |
| SCHEMBL19495183 | 0.66 | GAA (0.40) | ALDH1A1RAB9AMAOAMAOBPOLB | |
| SCHEMBL16961724 | 0.62 | CES2 (0.48) | CES2CES1RAB9AMAOAMAOB | |
| SCHEMBL16954373 | 0.62 | CES2 (0.58) | CES2CES1RAB9AMAOAMAOB | |
| SCHEMBL16957209 | 0.62 | CES2 (0.44) | CES2CES1RAB9AMAOAMAOB | |
| SCHEMBL6921313 | 0.61 | CES2 (0.52) | CES2CES1RAB9AMAOAMAOB | |
| SCHEMBL4790688 | 0.61 | CES2 (0.52) | CES2CES1RAB9AMAOAMAOB | |
| SCHEMBL5396300 | 0.61 | CES2 (0.43) | CES2CES1ALDH1A1RAB9AMAOA | |
| SCHEMBL16953066 | 0.60 | CES2 (0.56) | CES2CES1RAB9AMAOAMAOB | |
| SCHEMBL8222762 | 0.60 | CES2 (0.50) | CES2CES1RAB9AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2804859-B1 | NOVEL FAP INHIBITORS | UNIV ANTWERPEN (BE) | 2019-06-12 | — | — | EP | disclosed |