Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29337015 | 0.80 | SMN1; SMN2 (0.36) | GAAPOLBHDAC3HDAC1HDAC2 | |
| SCHEMBL21428975 | 0.69 | CES2 (0.35) | GAAPOLBMAPTRAB9AMAOA | |
| SCHEMBL21318856 | 0.69 | — | — | |
| SCHEMBL21101374 | 0.66 | CES2 (0.35) | POLBRAB9AMAOAMAOBTRPA1 | |
| SCHEMBL22172336 | 0.64 | MAOA (0.46) | HDAC3HDAC1HDAC2MAOAMAOB | |
| SCHEMBL24631062 | 0.63 | SMN1; SMN2 (0.34) | GAAPOLBMAPTRAB9ALMNA | |
| SCHEMBL20434140 | 0.62 | — | — | |
| Alcohol SCHEMBL28041790 | 0.62 | ACHE (0.53) | LMNAHTR7TRPA1ALDH1A1 | |
| SCHEMBL10413993 | 0.61 | MAOA (0.55) | RAB9AMAOAMAOBLMNAHTR7 | |
| SCHEMBL14594223 | 0.61 | ALDH1A1 (0.57) | GAAPOLBHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935271-B1 | NOVEL SUBSTITUTED IMIDAZOLES AS CASEIN KINASE 1 / INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-10-25 | — | — | EP | disclosed |