Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.52 |
| ▸ | CCR8 | P51685 | 3/20 | 0.52 |
| ▸ | CCR5 | P51681 | 2/20 | 0.52 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.41 |
| ▸ | COPS5 | Q92905 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 3/20 | 0.39 |
| ▸ | NOS2 | P35228 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19039387 | 0.82 | PSMD14 (0.49) | CCR1CCR8CCR5PSMD14COPS5 | |
| SCHEMBL16919865 | 0.82 | LIMK1 (0.56) | CCR1CCR8CCR5PSMD14COPS5 | |
| SCHEMBL16693486 | 0.79 | CCR1 (0.38) | CCR1CCR8CCR5PSMD14COPS5 | |
| SCHEMBL10200847 | 0.78 | CCR1 (0.45) | CCR1CCR8CCR5PSMD14COPS5 | |
| SCHEMBL13209223 | 0.76 | LIMK1 (0.51) | CCR1CCR8CCR5PSMD14COPS5 | |
| SCHEMBL12203219 | 0.75 | CCR1 (0.65) | CCR1CCR8CCR5PSMD14COPS5 | |
| SCHEMBL16919875 | 0.75 | CLK1 (0.55) | CCR1CCR8CCR5PSMD14COPS5 | |
| SCHEMBL14980103 | 0.75 | PDPK1 (0.47) | CCR1CCR8CCR5PSMD14COPS5 | |
| SCHEMBL16919869 | 0.73 | CCR1 (0.41) | CCR1CCR8CCR5PSMD14COPS5 | |
| SCHEMBL16919864 | 0.73 | CCR1 (0.41) | CCR1CCR8CCR5PSMD14COPS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2993215-B1 | Azabenzimidazo[2,1-a]benzimidazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2019-06-19 | — | — | EP | disclosed |