Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.62 |
| ▸ | QDPR | P09417 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 5/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12716503 | 0.93 | KDM1A (0.55) | KDM1AQDPRPDE4APDE4BPDE4C | |
| SCHEMBL15180853 | 0.89 | KDM1A (0.51) | KDM1AQDPRPDE4APDE4BPDE4C | |
| SCHEMBL31063362 | 0.88 | KDM1A (0.54) | KDM1AQDPRPDE4APDE4BPDE4C | |
| SCHEMBL22279844 | 0.88 | HTR2C (0.54) | KDM1AQDPRPDE4BSLC6A2SLC6A4 | |
| SCHEMBL10302897 | 0.87 | KDM1A (0.50) | KDM1AQDPRPDE4APDE4BPDE4C | |
| SCHEMBL28769188 | 0.87 | KDM1A (0.50) | KDM1AQDPRPDE4APDE4BPDE4C | |
| SCHEMBL28769187 | 0.87 | KDM1A (0.50) | KDM1AQDPRPDE4APDE4BPDE4C | |
| SCHEMBL23605276 | 0.87 | QDPR (0.64) | KDM1AQDPRPDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL4892688 | 0.87 | HTR2C (0.55) | KDM1AQDPRPDE4BSLC6A2SLC6A4 | |
| SCHEMBL16892013 | 0.85 | KDM1A (0.51) | KDM1AQDPRPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10330673-B2 | Fluorescent chemical sensor for biological amines | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2019-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10330673-B2 | Fluorescent chemical sensor for biological amines | ADRB3, SLC18A1, AOC3 | KDM1A 2401/4885QDPR 1815/4885PDE4A 94/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.