Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MMP14 | P50281 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9486107 | 0.81 | KDM4E (0.50) | NR4A2KDM4EALDH1A1SMN1; SMN2HTT | |
| SCHEMBL318769 | 0.81 | NR4A2 (0.68) | NR4A2KDM4EALDH1A1SMN1; SMN2HTT | |
| SCHEMBL29410781 | 0.81 | NR4A2 (0.68) | NR4A2KDM4EALDH1A1SMN1; SMN2HTT | |
| SCHEMBL27876058 | 0.78 | KDM4E (0.47) | NR4A2KDM4EALDH1A1SMN1; SMN2HTT | |
| SCHEMBL3271557 | 0.76 | PSMD14 (0.61) | NR4A2KDM4EALDH1A1SMN1; SMN2HTT | |
| SCHEMBL1195473 | 0.76 | KDM4E (0.46) | NR4A2KDM4EALDH1A1SMN1; SMN2HTT | |
| SCHEMBL1245479 | 0.76 | KDM4E (0.54) | NR4A2KDM4EALDH1A1SMN1; SMN2HTT | |
| SCHEMBL10009591 | 0.76 | NR4A2 (1.00) | NR4A2KDM4EALDH1A1SMN1; SMN2HTT | |
| SCHEMBL1025455 | 0.76 | NR4A2 (0.61) | NR4A2KDM4EALDH1A1SMN1; SMN2HTT | |
| SCHEMBL18848335 | 0.76 | HTR1A (0.56) | KDM4EALDH1A1SMN1; SMN2HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2804859-B1 | NOVEL FAP INHIBITORS | UNIV ANTWERPEN (BE) | 2019-06-12 | — | — | EP | disclosed |