Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LSS | P48449 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23177943 | 0.82 | KDM4E (0.36) | POLBHPGD | |
| SCHEMBL9196414 | 0.79 | CYP1A2 (0.54) | CYP1A2LMNAMAPK1HTTMAPT | |
| SCHEMBL25564727 | 0.78 | FFAR4 (0.35) | PIM1 | |
| SCHEMBL25025847 | 0.78 | FFAR4 (0.35) | PIM1 | |
| SCHEMBL24775798 | 0.77 | SAT1 (0.38) | — | |
| SCHEMBL22601341 | 0.76 | CYP1A2 (0.36) | CYP1A2HTTLSS | |
| SCHEMBL17682168 | 0.75 | APLNR (0.36) | PIM1 | |
| SCHEMBL19304169 | 0.75 | CYP1A2 (0.54) | CYP1A2LMNAMAPK1HTTMAPT | |
| SCHEMBL23323295 | 0.73 | SLC6A4 (0.31) | PIM1 | |
| SCHEMBL23323125 | 0.73 | SLC6A4 (0.31) | PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019111980-A1 | CYCLOALKYLACETIC ACID-TYPE DIAMIDE DERIVATIVE | 第一三共株式会社 | 2019-06-13 | — | — | WO | disclosed |