Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 14/20 | 0.65 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.53 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316867 | 0.98 | PTGS2 (0.66) | PTGS2MTNR1AMTNR1BSOAT1CYSLTR2 | |
| SCHEMBL423421 | 0.95 | PTGS2 (0.66) | PTGS2MTNR1AMTNR1B | |
| SCHEMBL10144147 | 0.87 | PTGS2 (0.62) | PTGS2MTNR1AMTNR1B | |
| SCHEMBL30753695 | 0.85 | MTNR1A (0.62) | PTGS2MTNR1AMTNR1B | |
| SCHEMBL2284298 | 0.85 | MTNR1A (0.62) | PTGS2MTNR1AMTNR1B | |
| SCHEMBL10904132 | 0.82 | MTNR1A (0.53) | PTGS2MTNR1AMTNR1B | |
| SCHEMBL6041415 | 0.82 | MTNR1A (0.56) | PTGS2MTNR1AMTNR1B | |
| SCHEMBL15521629 | 0.80 | PTGS2 (0.48) | PTGS2SOAT1G6PD | |
| SCHEMBL4413192 | 0.79 | PTGS2 (0.72) | PTGS2MTNR1AMTNR1BCYSLTR2CYSLTR1 | |
| SCHEMBL13659627 | 0.79 | PTGS2 (1.00) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046736-B1 | ARYLSULFANYL COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2019-06-12 | — | — | EP | disclosed |