Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | CDC14B | O60729 | 2/20 | 0.36 |
| ▸ | CDC14A | Q9UNH5 | 2/20 | 0.36 |
| ▸ | PRKDC | P78527 | 4/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19195961 | 0.91 | ALOX5 (0.52) | ALOX5GGPS1MEN1CYP2C19KMT2A | |
| SCHEMBL21102409 | 0.83 | ALOX5 (0.48) | ALOX5GGPS1MEN1CYP2C19KMT2A | |
| SCHEMBL19195568 | 0.81 | HSP90AA1 (0.42) | ALOX5MEN1CYP2C19KMT2ANMUR2 | |
| SCHEMBL26469935 | 0.81 | NMUR2 (0.41) | ALOX5MEN1KMT2ANMUR2GABRP | |
| SCHEMBL20205297 | 0.81 | ALOX5 (0.56) | ALOX5GGPS1MEN1CYP2C19KMT2A | |
| SCHEMBL19132014 | 0.80 | NMUR2 (0.41) | ALOX5MEN1CYP2C19KMT2ANMUR2 | |
| SCHEMBL17806984 | 0.79 | ALOX5 (0.59) | ALOX5GGPS1PTGES2HDAC8PRKDC | |
| SCHEMBL21902338 | 0.78 | ALOX5 (0.46) | ALOX5GGPS1MEN1CYP2C19KMT2A | |
| SCHEMBL24941667 | 0.78 | ALOX5 (0.58) | ALOX5GGPS1PTGES2HDAC8PRKDC | |
| SCHEMBL19199971 | 0.78 | ALOX5 (0.53) | ALOX5GGPS1MEN1CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200308129-A1 | SUBSTITUTED AROMATIC AMINES FOR USE IN ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-10-01 | — | — | US | disclosed |
| WO-2019115577-A1 | SUBSTITUTED AROMATIC AMINES FOR USE IN ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2019-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200308129-A1 | SUBSTITUTED AROMATIC AMINES FOR USE IN ORGANIC ELECTROLUMINESCENT DEVICES | DDC, CHRM5, AFF2 | ALOX5 2670/4885GGPS1 2850/4885MEN1 1725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.