Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12202832 | 0.79 | NPC1 (0.41) | ALDH1A1TDP1MAPK1MAPTKMT2A | |
| SCHEMBL10614068 | 0.74 | ALDH1A1 (0.61) | ALDH1A1TDP1MAPK1TSHRHSD17B10 | |
| Azobenzene SCHEMBL28147224 | 0.72 | ALDH1A1 (0.67) | ALDH1A1TDP1MAPK1TSHRHSD17B10 | |
| SCHEMBL3312603 | 0.72 | ALDH1A1 (0.58) | ALDH1A1TDP1MAPK1TSHRHSD17B10 | |
| SCHEMBL3312600 | 0.72 | ALDH1A1 (0.58) | ALDH1A1TDP1MAPK1TSHRHSD17B10 | |
| Bromide SCHEMBL7592896 | 0.71 | ALDH1A1 (0.44) | ALDH1A1TDP1MAPK1TSHRHSD17B10 | |
| SCHEMBL509329 | 0.71 | TRPA1 (0.45) | ALDH1A1TDP1MAPK1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL7593693 | 0.71 | ALDH1A1 (0.44) | ALDH1A1TDP1MAPK1TSHRMAPT | |
| SCHEMBL24463678 | 0.71 | CYP2C9 (0.41) | ALDH1A1TDP1MAPK1TSHRMAPT | |
| SCHEMBL3078252 | 0.70 | ALDH1A1 (0.55) | ALDH1A1TDP1MAPK1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10322999-B2 | Oxindoles derivatives, preparation method thereof and pharmaceutical compositions for the prevention or treatment of cancer containing the same as an active ingredient | Research & Business Foundation Sungkyunkwan University (KR) | 2019-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10322999-B2 | Oxindoles derivatives, preparation method thereof and pharmaceutical compositions for the prevention or treatment of cancer containing the same as an active ingredient | ODC1, CCNI, CYP3A5 | ALDH1A1 884/4885TDP1 3472/4885MAPK1 4325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.