Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.83 |
| ▸ | BLM | P54132 | 1/20 | 0.83 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.83 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | INPPL1 | O15357 | 2/20 | 0.33 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.33 |
| ▸ | BTN3A1 | O00481 | 2/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.33 |
| ▸ | INPP5B | P32019 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ITPR3 | Q14573 | 3/20 | 0.32 |
| ▸ | ITPR2 | Q14571 | 1/20 | 0.32 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL31219450 | 0.96 | FDPS (0.91) | FDPSBLMTDP1SLC34A1CA4 | |
| Pyrophosphoric Acid SCHEMBL29634664 | 0.91 | — | — | |
| Pyrophosphoric Acid SCHEMBL3654 | 0.91 | — | — | |
| Pyrophosphoric Acid SCHEMBL8851914 | 0.91 | FDPS (1.00) | FDPSBLMTDP1SLC34A1CA4 | |
| Pyrophosphoric Acid SCHEMBL292348 | 0.91 | FDPS (1.00) | FDPSBLMTDP1SLC34A1CA4 | |
| Pyrophosphoric Acid SCHEMBL28612691 | 0.88 | FDPS (0.77) | FDPSBLMTDP1SLC34A1CA4 | |
| Pyrophosphoric Acid SCHEMBL23537746 | 0.87 | FDPS (0.91) | FDPSBLMTDP1SLC34A1CA4 | |
| Pyrophosphoric Acid SCHEMBL21145230 | 0.87 | FDPS (0.91) | FDPSBLMTDP1CA4INPPL1 | |
| Pyrophosphoric Acid SCHEMBL18825562 | 0.87 | FDPS (0.91) | FDPSBLMTDP1SLC34A1CA4 | |
| Pyrophosphoric Acid SCHEMBL21433694 | 0.87 | FDPS (0.91) | FDPSBLMTDP1SLC34A1CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507246-A1 | PROCESS FOR PRODUCING POTASSIUM CHLORIDE GRANULATES | K+S Aktiengesellschaft (DE) | 2019-07-10 | — | — | EP | disclosed |
| EP-3507244-A1 | METHOD FOR PRODUCING POTASSIUM CHLORIDE GRANULAR MATERIALS | K+S Aktiengesellschaft (DE) | 2019-07-10 | — | — | EP | disclosed |
| EP-3507245-A1 | METHOD FOR PRODUCING POTASSIUM CHLORIDE GRANULAR MATERIALS | K+S Aktiengesellschaft (DE) | 2019-07-10 | — | — | EP | disclosed |