Bicarbonate

Bicarbonate

SCHEMBL21110933

CCCCCCCCC(F)=C(F)F.O=C(O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.56
PPARG P37231 7/20 0.56
PPARD Q03181 7/20 0.56
PPARA Q07869 7/20 0.56
HDAC11 Q96DB2 5/20 0.56
TSHR P16473 4/20 0.56
PTPN1 P18031 3/20 0.56
ALDH1A1 P00352 2/20 0.56
TLR2 O60603 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
FABP4 P15090 2/20 0.56
KMT2A Q03164 2/20 0.56
SLC22A6 Q4U2R8 1/20 0.56
SLC22A8 Q8TCC7 1/20 0.56
MEN1 O00255 1/20 0.56
ESR1 P03372 1/20 0.56
ALOX15 P16050 1/20 0.56
PDE4A P27815 1/20 0.56
PDE3A Q14432 1/20 0.56
HSD17B10 Q99714 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6058330 0.91 CES2 (0.48) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL1268926 0.91 CES2 (0.48) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL372685 0.91 CES2 (0.48) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL10627690 0.88 CES2 (0.46) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL11600331 0.80 GPR84 (0.54) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL7154879 0.80 CES2 (0.52) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL7154882 0.80 CES2 (0.52) GPR84PPARGPPARDPPARAHDAC11
Decanoic Acid SCHEMBL30960770 0.79 GPR84 (0.81) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL5630583 0.78 FNTA (0.62) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL4331635 0.78 FNTA (0.62) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109643807-B Solid-liquid electrolyte for use in batteries 罗地亚经营管理公司 2022-11-01 CN disclosed
EP-3918656-A1 ELECTROLYTE Rhodia Operations (FR) 2021-12-08 EP disclosed
WO-2020157085-A9 ELECTROLYTE RHODIA OPERATIONS (FR) 2021-11-25 WO disclosed
CN-113678291-A Electrolyte 罗地亚经营管理公司 2021-11-19 CN disclosed
US-10916782-B2 Solid-liquid electrolyte for use in a battery SPECIALTY OPERATIONS FRANCE (FR) 2021-02-09 US disclosed
EP-3747068-A1 COMPOSITE ELECTROLYTE Rhodia Operations (FR) 2020-12-09 EP disclosed
CN-111566844-A Composite electrolyte 罗地亚经营管理公司 2020-08-21 CN disclosed
EP-3691015-A1 ELECTROLYTE Rhodia Operations (FR) 2020-08-05 EP disclosed
EP-3507850-B1 SOLID-LIQUID ELECTROLYTE FOR USE IN A BATTERY RHODIA OPERATIONS (FR) 2020-06-17 EP disclosed
US-20190221859-A1 SOLID-LIQUID ELECTROLYTE FOR USE IS A BATTERY SPECIALTY OPERATIONS FRANCE (FR) 2019-07-18 US disclosed
EP-3507850-A1 SOLID-LIQUID ELECTROLYTE FOR USE IN A BATTERY Rhodia Operations (FR) 2019-07-10 EP disclosed