Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10743065 | 0.84 | KDM4E (0.50) | HSD17B10MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL3401906 | 0.84 | KDM4E (0.52) | HSD17B10MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9379704 | 0.83 | ALDH1A1 (0.58) | HSD17B10MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL17475410 | 0.83 | KDM4E (0.51) | HSD17B10MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL3341252 | 0.82 | KDM4E (0.58) | HSD17B10MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9626251 | 0.81 | KDM4E (0.47) | HSD17B10MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5307312 | 0.81 | KDM4E (0.49) | HSD17B10MEN1KMT2AKDM4EALDH1A1 | |
| Cyclopropane SCHEMBL3447310 | 0.80 | ALDH1A1 (0.56) | HSD17B10MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7542900 | 0.79 | ALDH1A1 (0.46) | HSD17B10MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7542895 | 0.79 | ALDH1A1 (0.46) | HSD17B10MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019135010-A1 | TIACUMICIN DERIVATIVES AND THEIR USE AS ANTIBIOTICS | Universität Zürich (CH) | 2019-07-11 | — | — | WO | disclosed |
| EP-3508492-A1 | TIACUMICIN DERIVATIVES AND THEIR USE AS ANTIBIOTICS | Universität Zürich (CH) | 2019-07-10 | — | — | EP | disclosed |