Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | HPGD | P15428 | 6/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | TOP2A | P11388 | 4/20 | 0.58 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclopropane SCHEMBL3447310 | 0.98 | ALDH1A1 (0.56) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL3401906 | 0.90 | KDM4E (0.52) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL17475410 | 0.89 | KDM4E (0.51) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL10743065 | 0.88 | KDM4E (0.50) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL9379704 | 0.87 | ALDH1A1 (0.58) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL5307312 | 0.87 | KDM4E (0.49) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL9626251 | 0.85 | KDM4E (0.47) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL7557789 | 0.84 | ALDH1A1 (0.50) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL6714523 | 0.82 | HPGD (0.45) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL21111089 | 0.82 | HSD17B10 (0.51) | KDM4EHPGDHSD17B10ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000551-A1 | PROCESS FOR THE PREPARATION OF QUINOLINE ANTIBACTERIAL COMPOUNDS | ABBOTT LABORATORIES (US) | 1990-01-25 | — | — | WO | claimed |
| EP-0350950-A1 | Process for the preparation of quinoline antibacterial compounds | ABBOTT LABORATORIES (US) | 1990-01-17 | — | — | EP | claimed |
| US-20100094230-A1 | POLYMER MOLDING COMPOUNDS CONTAINING PARTIALLY NEUTRALIZED AGENTS | BAYER INNOVATION GMBH (DE) | 2010-04-15 | — | — | US | disclosed |