SCHEMBL21112005

SCHEMBL21112005

C=CC(=O)OCc1cccc(F)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.68
MMP1 P03956 1/20 0.52
MMP2 P08253 1/20 0.52
MMP9 P14780 1/20 0.52
MMP12 P39900 1/20 0.52
IDO1 P14902 2/20 0.50
AGXT P21549 2/20 0.50
KDM4E B2RXH2 3/20 0.49
GAA P10253 1/20 0.49
STAT1 P42224 1/20 0.49
RAB9A P51151 1/20 0.49
NR4A2 P43354 2/20 0.49
MAPT P10636 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
MAOB P27338 6/20 0.48
PARP10 Q53GL7 1/20 0.48
MAOA P21397 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL227301 0.88 HCAR2 (0.51) HCAR2MAPK1
SCHEMBL26041805 0.84 HCAR2 (0.49) HCAR2MMP1MMP2MMP9MMP12
SCHEMBL1898363 0.83 HCAR2 (0.48) HCAR2
SCHEMBL24270436 0.82 HCAR2 (0.47) HCAR2RAB9AMAPT
SCHEMBL9555012 0.82 HCAR2 (0.47) HCAR2MAPT
SCHEMBL2029341 0.82 IDO1 (0.51) HCAR2IDO1RAB9ACYP1A2CYP2D6
SCHEMBL24471036 0.81 ENPP2 (0.49) HCAR2MAPT
SCHEMBL1787511 0.81 HCAR2 (0.64) HCAR2MMP1MMP2MMP9MMP12
SCHEMBL28707037 0.81 HCAR2 (0.64) HCAR2MMP1MMP2MMP9MMP12
SCHEMBL19456975 0.81 HCAR2 (0.46) HCAR2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210024674-A1 POLYMER COMPOUND, COMPOSITION, INSULATING LAYER, AND ORGANIC THIN FILM TRANSISTOR SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-01-28 US disclosed
US-10676554-B2 Polymer compound, film obtained by hardening this polymer compound and electronic device comprising this film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-06-09 US disclosed
US-20190250510-A1 PHOTOSENSITIVE COMPOSITION AND ORGANIC THIN-FILM TRANSISTOR SUMITOMO CHEMICAL COMPANY, LIMITED. (JP) 2019-08-15 US disclosed
US-20190250509-A1 PHOTOSENSITIVE COMPOSITION AND ORGANIC THIN-FILM TRANSISTOR SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-08-15 US disclosed
US-20190211123-A1 POLYMER COMPOUND, FILM OBTAINED BY HARDENING THIS POLYMER COMPOUND AND ELECTRONIC DEVICE COMPRISING THIS FILM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-07-11 US disclosed