Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8679559 | 0.82 | CSNK1E (0.47) | SIGMAR1 | |
| SCHEMBL1627645 | 0.80 | CSNK1E (0.54) | SIGMAR1 | |
| SCHEMBL9007218 | 0.79 | EPHX1 (0.55) | SIGMAR1KCNH2 | |
| SCHEMBL4750483 | 0.77 | SIGMAR1 (0.46) | SIGMAR1KCNH2 | |
| SCHEMBL197085 | 0.75 | KCNH2 (0.50) | SIGMAR1KCNH2 | |
| SCHEMBL6286870 | 0.75 | SIGMAR1 (0.55) | SIGMAR1 | |
| SCHEMBL8634822 | 0.75 | SIGMAR1 (0.47) | SIGMAR1 | |
| SCHEMBL8634823 | 0.75 | EPHX1 (0.64) | SIGMAR1 | |
| SCHEMBL9556315 | 0.75 | TRPA1 (0.53) | SIGMAR1 | |
| Bromide SCHEMBL10928757 | 0.73 | SIGMAR1 (0.50) | SIGMAR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3501546-A2 | CYSTEINE DRUG CONJUGATES AND USE OF SAME | Seattle Genetics, Inc. (US) | 2019-06-26 | — | — | EP | disclosed |