SCHEMBL21113670

SCHEMBL21113670

CC(=O)c1cccc(/C(C)=N/c2cccc3cccnc23)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 9/20 0.50
KMT2A Q03164 9/20 0.50
NPC1 O15118 6/20 0.42
RAB9A P51151 5/20 0.42
ALDH1A1 P00352 3/20 0.42
KDR P35968 1/20 0.41
LMNA P02545 1/20 0.41
METAP2 P50579 1/20 0.41
METAP1 P53582 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
MAPT P10636 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
KDM4E B2RXH2 2/20 0.40
GAA P10253 1/20 0.40
HTT P42858 1/20 0.40
PARP1 P09874 1/20 0.40
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MAP4K4 O95819 1/20 0.39
CSNK1G2 P78368 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21113654 0.80 KMT2A (0.47) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL18543868 0.77 MAPT (0.52) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL19148270 0.76 KMT2A (0.62) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL21113671 0.75 MEN1 (0.47) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL21192707 0.73 TDP1 (0.44) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL16627978 0.73 TDP1 (0.44) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL18543937 0.72 MAPT (0.47) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL18543939 0.72 MAPT (0.47) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL24404252 0.71 PLAU (0.51) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL18943979 0.71 MEN1 (0.51) MEN1KMT2ANPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3517555-A1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF China Petroleum&Chemical Corporation (CN) 2019-07-31 EP claimed
US-20190211119-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST, AND USE THEREOF BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-07-11 US claimed
US-11325994-B2 Catalyst component for olefin polymerization, catalyst, and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2022-05-10 US disclosed
US-11325994-B2 Catalyst component for olefin polymerization, catalyst, and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2022-05-10 US disclosed
EP-3517555-A1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF China Petroleum&Chemical Corporation (CN) 2019-07-31 EP disclosed
US-20190211119-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST, AND USE THEREOF BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-07-11 US disclosed