SCHEMBL21113671

SCHEMBL21113671

CC(=O)c1cccc(CC=Nc2cccc3cccnc23)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.47
KMT2A Q03164 6/20 0.47
HDAC6 Q9UBN7 2/20 0.42
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
ALDH1A1 P00352 5/20 0.38
KDM4E B2RXH2 4/20 0.38
MAPT P10636 4/20 0.38
LMNA P02545 3/20 0.38
ESR1 P03372 1/20 0.38
POLB P06746 1/20 0.38
AGTR1 P30556 1/20 0.38
OPRM1 P35372 1/20 0.38
OPRD1 P41143 1/20 0.38
OPRK1 P41145 1/20 0.38
MAPK1 P28482 1/20 0.38
MAOB P27338 2/20 0.37
HTT P42858 1/20 0.37
MAOA P21397 1/20 0.37
IL4I1 Q96RQ9 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18489530 0.80 LMNA (0.45) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL21113655 0.78 KDM4E (0.39) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL21113670 0.75 MEN1 (0.50) MEN1KMT2AHDAC6NPC1RAB9A
SCHEMBL21113673 0.73 KMT2A (0.49) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL21113692 0.73 MAOB (0.48) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL21113701 0.73 KMT2A (0.41) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL28571885 0.73 KDM4E (0.49) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL21113629 0.72 MAOB (0.41) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL19148271 0.71 KDM4E (0.44) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL21113635 0.69 EPHX1 (0.39) KMT2ANPC1RAB9AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107868155-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-09-15 CN claimed
CN-107868149-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-07-24 CN claimed
CN-107868153-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-07-24 CN claimed
CN-107868154-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-07-24 CN claimed
EP-3517555-A1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF China Petroleum&Chemical Corporation (CN) 2019-07-31 EP claimed
US-20190211119-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST, AND USE THEREOF BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-07-11 US claimed
US-11325994-B2 Catalyst component for olefin polymerization, catalyst, and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2022-05-10 US disclosed
CN-107868155-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-09-15 CN disclosed
CN-107868149-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-07-24 CN disclosed
CN-107868153-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-07-24 CN disclosed
CN-107868154-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-07-24 CN disclosed
EP-3517555-A1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF China Petroleum&Chemical Corporation (CN) 2019-07-31 EP disclosed
US-20190211119-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST, AND USE THEREOF BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-07-11 US disclosed