SCHEMBL21113689

SCHEMBL21113689

CC(=O)c1cccc(/C(C)=N/c2ccc3ccccc3c2)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR3E A5X5Y0 2/20 0.46
HTR3B O95264 2/20 0.46
HTR3A P46098 2/20 0.46
HTR3D Q70Z44 2/20 0.46
HTR3C Q8WXA8 2/20 0.46
KDM4E B2RXH2 3/20 0.42
POLB P06746 1/20 0.42
SIGMAR1 Q99720 1/20 0.39
NPC1 O15118 5/20 0.38
RAB9A P51151 5/20 0.38
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
HSP90AA1 P07900 3/20 0.38
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.36
MAPT P10636 2/20 0.36
GAA P10253 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
IRAK4 Q9NWZ3 1/20 0.35
CES2 O00748 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18543866 0.92 HTR3E (0.53) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL21113637 0.84 HTR3E (0.40) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL21113696 0.83 KDM4E (0.44) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL21113709 0.81 MAP4K4 (0.47) KDM4EPOLBNPC1RAB9AKMT2A
SCHEMBL15890723 0.80 NOS3 (0.42) KDM4ENPC1RAB9AMEN1KMT2A
SCHEMBL24187390 0.79 MEN1 (0.49) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL24404236 0.79 PTGS1 (0.40) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL21113666 0.79 PTGS1 (0.40) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL24404253 0.78 KMT2A (0.50) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL21113672 0.78 KMT2A (0.50) HTR3EHTR3BHTR3AHTR3DHTR3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3517555-B1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2024-11-27 EP claimed
EP-3517555-A1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF China Petroleum&Chemical Corporation (CN) 2019-07-31 EP claimed
US-20190211119-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST, AND USE THEREOF BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-07-11 US claimed
EP-3517555-B1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2024-11-27 EP disclosed
US-11325994-B2 Catalyst component for olefin polymerization, catalyst, and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2022-05-10 US disclosed
US-11325994-B2 Catalyst component for olefin polymerization, catalyst, and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2022-05-10 US disclosed
EP-3517555-A1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF China Petroleum&Chemical Corporation (CN) 2019-07-31 EP disclosed
US-20190211119-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST, AND USE THEREOF BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-07-11 US disclosed